Results 21 to 30 of about 2,444,251 (292)

Placental dysfunction influences fetal monocyte subpopulation gene expression in preterm birth

open access: yesJCI Insight, 2022
The placenta is the primary organ for immune regulation, nutrient delivery, gas exchange, protection against environmental toxins, and physiologic perturbations during pregnancy.
Abhineet M. Sharma   +9 more
doaj   +1 more source

SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease

open access: yesThe Journal of Clinical Investigation, 2022
Vascular calcification (VC) is regarded as an important pathological change lacking effective treatment and associated with high mortality. Sirtuin 6 (SIRT6) is a member of the Sirtuin family, a class III histone deacetylase and a key epigenetic ...
Wenxin Li   +10 more
doaj   +1 more source

Kaposin-B enhances the PROX1 mRNA stability during lymphatic reprogramming of vascular endothelial cells by Kaposi's sarcoma herpes virus. [PDF]

open access: yes, 2010
Kaposi's sarcoma (KS) is the most common cancer among HIV-positive patients. Histogenetic origin of KS has long been elusive due to a mixed expression of both blood and lymphatic endothelial markers in KS tumor cells.
Kafka, Darren   +37 more
core   +1 more source

Transient expansion and myofibroblast conversion of adipogenic lineage precursors mediate bone marrow repair after radiation

open access: yesJCI Insight, 2022
Radiation causes a collapse of bone marrow cells and elimination of microvasculature. To understand how bone marrow recovers after radiation, we focused on mesenchymal lineage cells that provide a supportive microenvironment for hematopoiesis and ...
Leilei Zhong   +16 more
doaj   +1 more source

Confocal and multiphoton laser scanning microscopy provide 3-dimensional imaging of atherosclerotic plaques in apolipoprotein e-deficient mice [PDF]

open access: yes, 2009
Meeting Abstract from 10th Annual Conference on Arteriosclerosis, Thrombosis and Vascular Biology held in Washington, DC, on April 29 - May 01, 2009.
Golledge, Jonathan   +65 more
core   +1 more source

Vascular endothelial growth factor production and regulation in rodent and human pituitary tumor cells in vitro [PDF]

open access: yes, 2001
Angiogenesis, the formation of a new blood supply, is an essential step in tumorigenesis. Although vascular endothelial growth factor (VEGF) is known to be a very potent angiogenic factor in most solid tumors, little is known about its production and ...
Losa, Marco   +16 more
core   +1 more source

Noncoding RNAs in Vascular Cell Biology and Restenosis [PDF]

open access: yes, 2022
In-stent restenosis (ISR), characterised by ≥50% re-narrowing of the target vessel, is a common complication following stent implantation and remains a significant challenge to the long-term success of angioplasty procedures.
Xiao, Q   +3 more
core   +1 more source

Lymphatic vascular morphogenesis in development, physiology, and disease [PDF]

open access: yes, 2011
The lymphatic vasculature constitutes a highly specialized part of the vascular system that is essential for the maintenance of interstitial fluid balance, uptake of dietary fat, and immune response. Recently, there has been an increased awareness of the
Amélie Sabine   +6 more
core   +3 more sources

Neuropilin-1/GIPC1 signaling regulates α5β1 integrin traffic and function in endothelial cells [PDF]

open access: yes, 2009
Neuropilin 1 (Nrp1) is a coreceptor for vascular endothelial growth factor A165 (VEGF-A165, VEGF-A164 in mice) and semaphorin 3A (SEMA3A). Nevertheless, <i>Nrp1</i> null embryos display vascular defects that differ from those of mice lacking ...
Caccavari, Francesca   +43 more
core   +1 more source

Nuclear Receptors in Vascular Biology [PDF]

open access: yesCurrent Atherosclerosis Reports, 2015
Nuclear receptors sense a wide range of steroids and hormones (estrogens, progesterone, androgens, glucocorticoid, and mineralocorticoid), vitamins (A and D), lipid metabolites, carbohydrates, and xenobiotics. In response to these diverse but critically important mediators, nuclear receptors regulate the homeostatic control of lipids, carbohydrate ...
openaire   +2 more sources

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