Results 11 to 20 of about 2,444,251 (292)

Potential Associations between Vascular Biology and Hodgkin's Lymphoma: An Overview. [PDF]

Cancers (Basel), 2023
Hodgkin’s lymphoma (HL) is a lymphatic neoplasm typically found in the cervical lymph nodes. The disease is multifactorial, and in recent years, the relationships between various vascular molecules have been explored in the field of vascular ...
Rodrigues WF, Miguel CB, Abreu MCM, Neto JM, Oliveira CJF.   +4 more
europepmc   +2 more sources

The Paradigm Change of IL-33 in Vascular Biology. [PDF]

Int J Mol Sci, 2021
In this review, we focus on the actual understanding of the role of IL-33 in vascular biology in the context of the historical development since the description of IL-33 as a member of IL-1 superfamily and the ligand for ST2 receptor in 2005.
Demyanets S, Stojkovic S, Huber K, Wojta J.   +3 more
europepmc   +2 more sources

Intraluminal application of vascular endothelial growth factor enhances healing of microvascular anastomosis in a rat model [PDF]

, 2005
Background: Early reconstitution after injury to the endothelium is an important feature for reducing a number of vessel wall pathologies. We investigated the effect of vascular endothelial growth factor ( VEGF) and its impact on the vascular remodeling ...
Hollenberg, S. M., Shakibaei, M., Kossmehl, P., Faramarzi, S., Paul, M., Schulze-Tanzil, G., Infanger, M., Grosse, J., Grimm, D.   +8 more
core   +2 more sources

Mechanical regulation of epigenetic modifications in vascular biology and pathobiology

, 2021
[[abstract]]Shear stress and cyclic stretch are mechanical forces on the vessel wall exerted by blood flow and luminal pressure. These forces regulate gene expression and function in vascular cells, including endothelial cells (ECs) and smooth muscle ...
Wei, SY;Chiu, JJ
core   +1 more source

Bone-derived PDGF-BB drives brain vascular calcification in male mice

The Journal of Clinical Investigation, 2023
Brain vascular calcification is a prevalent age-related condition often accompanying neurodegenerative and neuroinflammatory diseases. The pathogenesis of large-vessel calcifications in peripheral tissue is well studied, but microvascular calcification ...
Jiekang Wang, Ching-Lien Fang, Kathleen Noller, Zhiliang Wei, Guanqiao Liu, Ke Shen, Kangping Song, Xu Cao, Mei Wan   +8 more
doaj   +1 more source

Vascular smooth muscle–specific YAP/TAZ deletion triggers aneurysm development in mouse aorta

JCI Insight, 2023
Inadequate adaption to mechanical forces, including blood pressure, contributes to development of arterial aneurysms. Recent studies have pointed to a mechanoprotective role of YAP and TAZ in vascular smooth muscle cells (SMCs).
Marycarmen Arévalo Martínez, Olivia Ritsvall, Joakim Armstrong Bastrup, Selvi Celik, Gabriel Jakobsson, Fatima Daoud, Christopher Winqvist, Anders Aspberg, Catarina Rippe, Lars Maegdefessel, Alexandru Schiopu, Thomas A. Jepps, Johan Holmberg, Karl Swärd, Sebastian Albinsson   +14 more
doaj   +1 more source

Complex consequences of Cantu syndrome SUR2 variant R1154Q in genetically modified mice

JCI Insight, 2021
Cantu syndrome (CS) is caused by gain-of-function (GOF) mutations in pore-forming (Kir6.1, KCNJ8) and accessory (SUR2, ABCC9) ATP-sensitive potassium (KATP) channel subunits, the most common mutations being SUR2[R1154Q] and SUR2[R1154W], carried by ...
Haixia Zhang, Alex Hanson, Tobias Scherf de Almeida, Christopher Emfinger, Conor McClenaghan, Theresa Harter, Zihan Yan, Paige E. Cooper, G. Schuyler Brown, Eric C. Arakel, Robert P. Mecham, Atilla Kovacs, Carmen M. Halabi, Blanche Schwappach, Maria S. Remedi, Colin G. Nichols   +15 more
doaj   +1 more source

Radiotherapy exposure directly damages the uterus and causes pregnancy loss

JCI Insight, 2023
Female cancer survivors are significantly more likely to experience infertility than the general population. It is well established that chemotherapy and radiotherapy can damage the ovary and compromise fertility, yet the ability of cancer treatments to ...
Meaghan J. Griffiths, Sarah A. Marshall, Fiona L. Cousins, Lauren R. Alesi, Jordan Higgins, Saranya Giridharan, Urooza C. Sarma, Ellen Menkhorst, Wei Zhou, Alison S. Care, Jacqueline F. Donoghue, Sarah J. Holdsworth-Carson, Peter A.W. Rogers, Evdokia Dimitriadis, Caroline E. Gargett, Sarah A. Robertson, Amy L. Winship, Karla J. Hutt   +17 more
doaj   +1 more source

Biology of Vascular Malformations of the Brain [PDF]

Stroke, 2009
Background and Purpose— This review discusses recent research on the genetic, molecular, cellular, and developmental mechanisms underlying the etiology of vascular malformations of the brain (VMBs), including cerebral cavernous malformation, sporadic brain arteriovenous malformation, and the ...
Leblanc GG, Golanov E, Awad IA, Young WL, Biology of Vascular Malformations of the Brain NINDS Workshop Collaborators:Awad I, Young WL, Berg M, Chopp M, Gale NW, Gunel M, Lo EH, Marchuk D, Rigamonti D, Tournier Lasserve E, Berg M, Blasig IE, Boudreau N, Chopp M, Gale NW, Ginsberg M, Jin K, Johnson GL, Kim H, Lawton MT, Letarte M, Li DY, Lo EH, Marchuk D, Mohr JP, Nishimura S, NOONAN, DOUGLAS, Pawlikowska L, Plate KH, Rigamonti D, Shenkar R, Tournier Lasserve E, Al Shahi Salman R, Ball KL, Clancy MS, Connolly SE Jr, Derry B, Faurobert E, Gault J, Golanov E, Hannegan L, Hashimoto T, Keep RF, Leblanc GG, Lee C, McCarty J, Morrison L, Ning M, Nunn MF, Oh SP, Plahn BK, Pratt CA, Pratt WB, Spatz M, Stapf C, Yang GY, Zhang J.   +60 more
openaire   +4 more sources

From vascular biology to vascular medicine

The EuroBiotech Journal, 2018
Cardiovascular disorders include various conditions characterized by morphological and functional defects of the heart and vascular system. Molecular biology techniques (in particular DNA sequencing) have recently offered new insights into the etiology ...
Paolacci Stefano, Rakhmanov Yeltay, Maltese Paolo Enrico, Bertelli Matteo   +3 more
doaj   +1 more source