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2002
Vascular calcification is a pathological calcification process. Its pathogenesis involves active mineralization by chondrogenic and osteogenic cells. Since cartilaginous metaplasia has been found in several vascular diseases, this process may represent one of vascular remodeling in response to vascular injury.
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Vascular calcification is a pathological calcification process. Its pathogenesis involves active mineralization by chondrogenic and osteogenic cells. Since cartilaginous metaplasia has been found in several vascular diseases, this process may represent one of vascular remodeling in response to vascular injury.
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Vascular calcification and bone disease: the calcification paradox
Trends in Molecular Medicine, 2009Vascular calcification or ectopic mineralization in blood vessels is an active, cell-regulated process, increasingly recognized as a general cardiovascular risk factor. Remarkably, ectopic artery mineralization is frequently accompanied by decreased bone mineral density or disturbed bone turnover.
Persy, Veerle, d' Haese, Patrick C.
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Preventing vascular calcification
Science, 2016Vascular Disease The arterial calcification that develops in patients with the genetic disease ACDC (arterial calcification due to deficiency of CD73) leads to peripheral ischemia. Cells from these patients have increased levels of an enzyme that degrades pyrophosphate, a compound that inhibits calcification. Jin et al.
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Pathophysiological mechanisms of vascular calcification
Annales de biologie clinique, 2015Vascular calcification (VC) is a degenerative pathology of the vessel wall. In the general population, VC appearance is associated with aging, but this pathology can also develop as a consequence of atherosclerosis, diabetes, inflammatory and chronic kidney disease.
Hénaut, Lucie+8 more
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Renal osteodystrophy and vascular calcification.
Journal of endocrinological investigation, 2009Chronic kidney disease (CKD) is characterized by phosphate retention and reduced synthesis of 1.25(OH)2-vitamin D stimulating parathyroid hyperplasia. These changes cause a complex osteopathy, defined as renal osteodystrophy, and vascular calcification. Renal osteodystrophy increases the risk of fracture and causes deformities and disability.
T. Arcidiacono+7 more
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Vascular calcification and magnesium [PDF]
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The neuroregulation of vascular calcification
Journal of Molecular and Cellular Cardiology, 2020Rui Yang+4 more
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