Results 101 to 110 of about 10,950,819 (369)
Vascular Inflammation and Oxidative Stress: Major Triggers for Cardiovascular Disease
Oxidative Medicine and Cellular Longevity, 2019 Cardiovascular disease is a leading cause of death and reduced quality of life, proven by the latest data of the Global Burden of Disease Study, and is only gaining in prevalence worldwide.
S. Steven +10 more
semanticscholar +1 more source
Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis
FEBS Open Bio, EarlyView.Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu +6 more
wiley +1 more source
Homocysteine and vascular disease
Journal of British Surgery, 1995 Abstract There is increasing evidence that a raised blood level of homocysteine (HC) is a risk factor for premature atherosclerosis. With a gene frequency between one in 70 and one in 200 this condition may be more common than previously thought.
Jamie Y. Jeremy +2 more
openaire +3 more sources
Circulation, 2003 Our population is aging; in the United States today there are 35 million people 65 years of age or older. That number will double by the year 2030 (Figure 1).
E. Lakatta, D. Levy
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran +3 more
wiley +1 more source
Greedy Graph Searching for Vascular Tracking in Angiographic Image Sequences [PDF]
arXiv, 2018 Vascular tracking of angiographic image sequences is one of the most clinically important tasks in the diagnostic assessment and interventional guidance of cardiac disease. However, this task can be challenging to accomplish because of unsatisfactory angiography image quality and complex vascular structures. Thus, this study proposed a new greedy graph
arxiv
Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
Aging and Cancer, EarlyView.This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal +8 more
wiley +1 more source
Aging and Cancer, EarlyView.Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley +1 more source
Renal Replacement Therapy, 2020 Background Endothelial dysfunction starts at an earlier stage in patients with chronic kidney disease (CKD), and induces macro- and microcirculatory impairments.
Takayasu Ohtake +8 more
doaj +1 more source
MicroRNAs in Vascular Biology and Vascular Disease [PDF]
Journal of Cardiovascular Translational Research, 2010 MicroRNAs (miRNAs) have emerged as a novel class of endogenous, small, non-coding RNAs that negatively regulate over 30% of genes in a cell via degradation or translational inhibition of their target mRNAs. Functionally, an individual miRNA is important as a transcription factor because it is able to regulate the expression of its multiple target genes.
openaire +2 more sources