Results 91 to 100 of about 2,456,717 (314)

Skeletal immaturity, rostral sparing, and disparate hip morphologies as biomechanical causes for Legg-Calvé-Perthes’ disease [PDF]

, 2016
Legg-Calvé-Perthes' (Perthes') disease is a developmental disease of the hip joint that may result in numerous short and long term problems. The etiology of the disease remains largely unknown, but the mechanism is believed to be vascular and/or ...
Acheson, Acheson, Adler, Allen, Anderson, Arie, Atsumi, Bahmanyar, Barker, Beals, Berg, Bergmann, Bergmann, Bergmann, Bohr, Brown, Bull, Burwell, Burwell, Caffey, Calvé, Camargo, Cameron, Canavese, Cannon, Catterall, Catterall, Choo, Chung, Churchill, Coyle, Crock, Currey, Danforth, Delclaux, Dillman, Donohue, Douglass, Duff, Ebong, Eckerwall, Edvardsen, Eijer, Eijer, Emr, Ezoe, Faraj, Fisher, García Mata, Gaskin, Gautier, Girdany, Goff, Gordon, Gray, Grzegorzewski, Guembecker, Güngör, Hailer, Hall, Hall, Hall, Hall, Hall, Hall, Harrison, Harrison, Harrison, Herndon, Herring, Herring, Hirano, Hofstaetter, Hong, Inoue, Isaac, Iwasaki, Joseph, Joseph, Joseph, Joseph, Kallio, Kamegaya, Kandzierski, Kataoka, Katz, Katz, Kawahara, Kawahara, Kealey, Kealey, Kemp, Kenet, Kim, Kim, Kim, Kim, Kitoh, Koob, Kristmundsdottir, Kristmundsdottir, Kristmundsdottir, Krul, Lappin, Laron, Larson, Lauritzen, Lee, Legg, Ljunggren, Lloyd-Roberts, Loder, Loder, Lubovsky, Madan, Margetts, McQuade, Mickelson, Moberg, Molloy, Moseley, Moulton, Nelitz, O'Higgins, Ogden, Osman, Osorio, Park, Perry, Perry, Perry, Perry, Perry, Perry, Perry, Perry, Perry, Perthes, Pillai, Pringle, Purry, Rab, Ralston, Rao, Rayfield, Rayner, Reynolds, Richmond, Rowe, Ruff, Salmaso, Salmingo, Salter, Sankar, Sharma, Shore, Smedley, Smith, Stuart, Stulberg, Suehiro, Suehiro, Tanner, Tardieu, Tardieu, Terjesen, Thompson, Thompson, Théron, Tomita, Toogood, Trueta, Tucker, Tutt, Ueo, Upadhyay, Upadhyay, Vasseur, Vaverka, Vila-Verde, Vosmaer, Wang, Weiner, Wiig, Wiig, Wijesekera, Winkleby, Wright, Wynne-Davies, Yoshida, Zarco, Zhang   +191 more
core   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Aberrant oligodendroglial-vascular interactions disrupt the blood-brain barrier, triggering CNS inflammation. [PDF]

, 2019
Disruption of the blood-brain barrier (BBB) is critical to initiation and perpetuation of disease in multiple sclerosis (MS). We report an interaction between oligodendroglia and vasculature in MS that distinguishes human white matter injury from normal ...
Baranzini, Sergio E, Chan, Jonah R, Fancy, Stephen PJ, Hoi, Kimberly K, Huang, Nanxin, Kim, Kicheol, Niu, Jianqin, Tsai, Hui-Hsin, Xiao, Lan, Yu, Guangdan   +9 more
core  

Intracranial dural arteriovenous fistula successfully treated by combined open-endovascular procedure [PDF]

, 2010
Intracranial dural arteriovenous fistulas constitute a rare though potentially devastating disease. Because the arterial (high-pressure) blood flow drains directly into the low-pressure venous system, there is a high risk of bleeding and associated ...
DE KEUKELEIRE, KATRIEN, Defreyne, Luc, Hallaert, Giorgio, Van Roost, Dirk, Vanhauwaert, Dimitri J   +4 more
core   +2 more sources

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Differential neuropsychological profiles in Parkinsonian patients with or without vascular lesions. [PDF]

, 2010
The purpose of this study is to compare the neuropsychological profile of patients affected by parkinsonism and vascular lesions to that in patients with PD alone (PD) and to evaluate whether the brain vascular lesion load is associated with ...
Antonini A, BARONE, PAOLO, BILO, LEONILDA, De Gaspari D, SANTANGELO, Gabriella, Trojano L, VITALE, CARMINE   +6 more
core  

Human tribbles-1 controls proliferation and chemotaxis of smooth muscle cells via MAPK signaling pathways [PDF]

, 2007
Migration and proliferation of smooth muscle cells are key to a number of physiological and pathological processes, including wound healing and the narrowing of the vessel wall.Previous work has shown links between inflammatory stimuli and vascular ...
Agnes Czibula, Andrea R. King, Anthony G. Wilson, Bonventre, Che, Choukroun, David C. Crossman, Du, Emily Heath, Endre Kiss-Toth, Force, Goldschmidt, Grosshans, Hegedus, Hegedus, Hongtao Guan, Hye Youn Sung, Iynedjian, Jones, Ju, Katalin Eder, King, Kiss-Toth, Kiss-Toth, Kiss-Toth, Koo, Lai, Levchenko, Li, Majesky, Mata, McCarthy, Michnick, Mii, Morton, Ohoka, Remy, Remy, Robinson, S. Kim Suvarna, Saka, Sato, Satterthwaite, Schwarzer, Seher, Sheila E. Francis, Stary, Stary, Stary, Steven K. Dower, Surapisitchat, Takeishi, Touyz, Warner, Wilkin, Xia, Yamakawa, Yang, Yue   +58 more
core   +1 more source

Physician perspectives on pulmonary hypertension in ILD: results of a cases-based survey

BMC Pulmonary Medicine
Background Pulmonary hypertension (PH) complicates the course of patients with interstitial lung disease (ILD) in 30–55% of cases and is associated with increased morbidity and mortality. The optimal timing of diagnostic right heart catheterization (RHC)
Ho Cheol Kim, Christopher S. King, Christopher Thomas, Vikramjit Khangoora, Osman Malik, Jared Wilkinson, Shambhu Aryal, Anju Singhal, Alan Nyquist, Oksana A. Shlobin, Steven D. Nathan   +10 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source