Results 111 to 120 of about 11,970,410 (409)

New insights into the biomechanics of Legg-Calvé-Perthes’ disease: The role of epiphyseal skeletal immaturity in vascular obstruction [PDF]

, 2018
ObjectivesLegg–Calvé–Perthes’ disease (LCP) is an idiopathic osteonecrosis of the femoral head that is most common in children between four and eight years old.
Dobson, C. A., Fagan, M. J., Perry, D., Pinheiro, M.   +3 more
core   +1 more source

Early pulmonary vascular disease in preterm infants at risk for bronchopulmonary dysplasia.

American Journal of Respiratory and Critical Care Medicine, 2015
RATIONALE Pulmonary hypertension (PH) is associated with poor outcomes among preterm infants with bronchopulmonary dysplasia (BPD), but whether early signs of pulmonary vascular disease are associated with the subsequent development of BPD or PH at 36 ...
P. Mourani, M. Sontag, A. Younoszai, Joshua I. Miller, J. Kinsella, C. Baker, B. Poindexter, D. Ingram, S. Abman   +8 more
semanticscholar   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Association of Systemic Inflammation With Retinal Vascular Caliber in Patients With AIDS. [PDF]

, 2019
PurposeTo evaluate relationships among retinal vascular caliber and biomarkers of systemic inflammation in patients with AIDS.MethodsA total of 454 participants with AIDS had retinal vascular caliber (central retinal artery equivalent and central retinal
Cheu, Ryan, Danis, Ronald P, Hunt, Peter W, Jabs, Douglas A, Jones, Norman, Klatt, Nichole R, Milush, Jeffrey M, Pak, Jeong Won, Trang, Garrett, Van Natta, Mark L   +9 more
core   +1 more source

Venous anomalies as potentially lethal risk factors during ordinary catheterization

Veins and Lymphatics, 2015
Venous malformations are rare but possible findings too, constituting a further risk factor for central venous catheter procedures. Herein we describe a case of death because of an innominate vein perforation by a catheter that incidentally was tucked ...
Savino Occhionorelli, Sergio Gianesini, Lorenzo Marinelli, Marianna Daniele, Sara Chierici, Paolo Zamboni   +5 more
doaj   +1 more source

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

Peripheral Vascular Disease

Home Healthcare Now, 2020
Peripheral vascular disease (PVD) is a leading health concern in the United States, with an estimated prevalence of 8.5 million. The incidence of PVD is growing due to increasing rates of obesity and diabetes, as well as an aging population. Peripheral vascular disease is categorized as either venous, arterial, or mixed.
Mellisa Hall, Constance F. Swenty
openaire   +3 more sources

Three dimensional rotational angiography imaging of double aortic arch vascular ring [PDF]

, 2013
Three dimensional (3D) rotational angiography is a technique used increasingly for imaging in congenital heart disease. Here the use of this technique for imaging of double aortic arch vascular ring is described and the advantages of this modality. are
Coren, J. S., Coyle, J. C., Ge, Shuping, Mesia, Cesar I., Moulick, Achintya, Patel, Brijesh, Poe, E., Rosenbloom, C., Stevens, R. M., Toib, A.   +9 more
core   +1 more source

Minimally Invasive Optical Biopsy for Oximetry [PDF]

, 2017
The study of localised oxygen saturation in blood vessels can shed light on the etiology and progression of many diseases with which hypoxia is associated.
Brewer, James M., Harvey, Andrew R., van der Putten, Marieke A.   +2 more
core   +1 more source

Idiopathic Pulmonary Fibrosis, Today and Tomorrow: Certainties and New Therapeutic Horizons

Pulmonary Therapy
Idiopathic pulmonary fibrosis (IPF) represents a clinical and therapeutic challenge characterized by progressive fibrosis and destruction of the lung architecture.
Giacomo Giulianelli, Elisabetta Cocconcelli, Giordano Fiorentù, Nicol Bernardinello, Elisabetta Balestro, Paolo Spagnolo   +5 more
doaj   +1 more source