Results 241 to 250 of about 2,456,717 (314)

A New 3D Colon on a Chip to Decipher the Influence of Mechanical Forces on the Physiological Cellular Ecosystem

Advanced Healthcare Materials, EarlyView.
To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery, Lauriane Gérémie, Julie Brun, Lucas Chassatte, Giacomo Gropplero, Réda Bouras, Jieun Choo, Bertrand Cinquin, Alba Marcellan, Danijela Matic Vignjevic, Stéphanie Descroix   +10 more
wiley   +1 more source

Long-term impact of cholecystectomy on myocardial infarction, ischemic cerebrovascular accident, and peripheral vascular disease: insights from a nationwide analysis. [PDF]

Trauma Surg Acute Care Open
Messer N, Rov A, Lahat G, Nizri E, Hornik-Lurie T, Kanani F, Yuval JB, Abu Abeid A, Lessing Y, Tsur AM, Chen J.   +10 more
europepmc   +1 more source

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

Advanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan, Jose Yeste, Mar Alvarez, Denise Marrero, Laura Casado‐Medina, Yvonne Richaud‐Patin, Olalla García‐Iglesias, Jagoda Litowczenko, Alba Morillas Garcia, Anton Guimerà, Xavi Illa, Rosa Villa, Angel Raya   +12 more
wiley   +1 more source

Cathepsin B as a potential serum biomarker for early diagnosis and progression of diabetic foot ulcer complicated with peripheral vascular disease. [PDF]

Sci Rep
Jin Y, Yao Y, Lin Y, Zhong J, Kong X, Liu Y, Li Y, Qiao J, Zhai A, Bi C.   +9 more
europepmc   +1 more source

Female patients with vascular disease receive less medical optimization despite more health care utilization. [PDF]

J Vasc Surg
Lowenkamp MN, Nassereldine H, Iams A, Tzeng E, Reitz KM.   +4 more
europepmc   +1 more source

Prevalence, Clinical Characteristics and Prognosis of Vascular Disease in Valvular Heart Surgery: A Multi-Centre Study. [PDF]

Glob Heart
Zhu CY, Zhang JN, Tse YK, Ren QW, Huang JY, Yu SY, Guo R, Gu WL, Chan DT, Lip GYH, Yiu KH.   +10 more
europepmc   +1 more source

Atherogenic index of plasma and subclinical vascular disease: predictive value for coronary and carotid atherosclerosis in a health screening population. [PDF]

Lipids Health Dis
Li XW, Shuai P, Huang XC, Mou Y, He PY.
europepmc   +1 more source

Treatment of a severe vascular disease using a bespoke CRISPR-Cas9 base editor in mice. [PDF]

Nat Biomed Eng
Alves CRR, Das S, Krishnan V, Ha LL, Fox LR, Stutzman HE, Shamber CE, Kalailingam P, McCarthy S, Lino Cardenas CL, Fong CE, Imai T, Mitra S, Yun S, Wood RK, Benning FMC, Roh K, Lawton J, Kim N, Silverstein RA, Ferreira da Silva J, de la Cruz D, Richa R, Xie J, Gray-Edwards HL, Malhotra R, Chung DY, Chao LH, Tsai SQ, Maguire CA, Lindsay ME, Kleinstiver BP, Musolino PL.   +32 more
europepmc   +1 more source

Dyslipidaemia and inflammation are risks for subclinical atherosclerotic vascular disease among chronic kidney failure patients in South Africa. [PDF]

PLoS One
Oguntola SO, Hassan MO, Duarte R, Dickens C, Dix-Peek T, Snyman T, Moodley K, Olorunfemi G, Vachiat A, Manga P, Naicker S.   +10 more
europepmc   +1 more source