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Vascular Diseases and Gangliosides [PDF]
Vascular diseases, such as myocardial infarction and cerebral infarction, are most commonly caused by atherosclerosis, one of the leading causes of death worldwide. Risk factors for atherosclerosis include lifestyle and aging. It has been reported that lifespan could be extended in mice by targeting senescent cells, which led to the suppression of ...
Norihiko Sasaki, Masashi Toyoda
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Insulin resistance is associated with subclinical vascular disease in humans
Insulin resistance is associated with subclinical vascular disease that is not justified by conventional cardiovascular risk factors, such as smoking or hypercholesterolemia.
María M. Adeva-Andany+4 more
semanticscholar +1 more source
Backgrounds Mounting evidences have highlighted the association between metabolites and cardiovascular diseases. Our previous works have demonstrated that circulating metabolite, trimethylamine oxide, was associated with prognosis of patients with ...
Yicheng Yang+8 more
doaj +1 more source
Monocytes play a vital role in the development of cardiovascular diseases. Type 2 diabetes mellitus (T2DM) is a major CVD risk factor, and T2DM-induced aberrant activation and enhanced migration of monocytes is a vital pathomechanism that leads to ...
Marc Dorenkamp+7 more
doaj +1 more source
Osteopontin in Vascular Disease: Friend or Foe?
Inflammatory cytokines are necessary for an acute response to injury and the progressive healing process. However, when this acute response does not resolve and becomes chronic, the same proteins that once promoted healing then contribute to chronic ...
Zoe S Lok, A. Lyle
semanticscholar +1 more source
Lymphedema is a progressive condition that can reach an extreme, debilitating stage known as elephantiasis. This case presents a 57-year-old man with stage III by International Society of Lymphology (ISL) lower limb primary lymphedema diagnosed by a ...
Bruno Soggia+4 more
doaj +1 more source
Clinical Applications of Endobronchial Ultrasound (EBUS) Scope: Challenges and Opportunities
Endobronchial Ultrasound (EBUS) has been widely used to stage lung tumors and to diagnose mediastinal diseases. In the last decade, this procedure has evolved in several technical aspects, with new tools available to optimize tissue sampling and to ...
Davide Biondini+8 more
doaj +1 more source
Inhaled Nanoparticles Accumulate at Sites of Vascular Disease
The development of engineered nanomaterials is growing exponentially, despite concerns over their potential similarities to environmental nanoparticles that are associated with significant cardiorespiratory morbidity and mortality. The mechanisms through
Mark R. Miller+17 more
semanticscholar +1 more source
Perivascular Adipocytes in Vascular Disease.
Perivascular adipocytes residing in the vascular adventitia are recognized as distinct endocrine cells capable of responding to inflammatory stimuli and communicating with the sympathetic nervous system and adjacent blood vessel cells, thereby releasing ...
Ha Won Kim+2 more
semanticscholar +1 more source
Homocysteine and vascular disease
For more than 20 years, moderately raised concentrations of total homocysteine have been associated with an increased risk of atherothrombotic vascular events but only recently has evidence mounted to suggest that the association may be causal. The association is independent of other factors, it is fairly consistent across many studies, it is strong ...
Graeme J. Hankey, John W. Eikelboom
openaire +4 more sources