Results 11 to 20 of about 2,456,717 (314)

NAD+ exhaustion by CD38 upregulation contributes to blood pressure elevation and vascular damage in hypertension

Signal Transduction and Targeted Therapy, 2023
Hypertension is characterized by endothelial dysfunction and arterial stiffness, which contribute to the pathogenesis of atherosclerotic cardiovascular diseases.
Yumin Qiu, Shiyue Xu, Xi Chen, Xing Wu, Zhe Zhou, Jianning Zhang, Qiang Tu, Bing Dong, Zhefu Liu, Jiang He, Xiaoyu Zhang, Shuangshuang Liu, Chen Su, Hui Huang, Wenhao Xia, Jun Tao   +15 more
doaj   +1 more source

Application of a Novel Common-Iliac-Artery Skirt Technology (CST) in Treating Challenge Aorto-Iliac or Isolated Iliac Artery Aneurysms

Frontiers in Cardiovascular Medicine, 2021
Purpose: To report a novel common-iliac-artery skirt technology (CST) in treating challenge iliac artery aneurysms.Methods: When required healthy landing zone of common iliac artery (CIA) is not available, CST is a strategy to exclude the internal iliac ...
Lunchang Wang, Lunchang Wang, Chang Shu, Chang Shu, Chang Shu, Quanming Li, Quanming Li, Ming Li, Ming Li, Hao He, Hao He, Xin Li, Xin Li, Yin Shi, Jian Qiu, Jian Qiu, Tun Wang, Tun Wang, Chenzi Yang, Chenzi Yang, Mo Wang, Mo Wang, Jiehua Li, Jiehua Li, Hui Wang, Hui Wang, Likun Sun, Likun Sun   +27 more
doaj   +1 more source

Drug treatment of hypertension: focus on vascular health [PDF]

, 2016
Hypertension, the most common preventable risk factor for cardiovascular disease and death, is a growing health burden. Serious cardiovascular complications result from target organ damage including cerebrovascular disease, heart failure, ischaemic heart
Cameron, Alan C., Lang, Ninian N., Touyz, Rhian M.   +2 more
core   +1 more source

The impact of type 2 diabetes and Microalbuminuria on future cardiovascular events in patients with clinically manifest vascular disease from the Second Manifestations of ARTerial Disease (SMART) study [PDF]

, 2008
Aims Type 2 diabetes mellitus and microalbuminuria are important risk factors for cardiovascular disease (CVD). Whether these two complications are important and independent risk factors for future CVD events in a high-risk population with clinically ...
Algra, A., Graaf, Y., van der, Soedamah-Muthu, S.S., Visseren, F.L.J.   +3 more
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Statin usage, vascular diagnosis and vascular risk factors in Parkinson's disease [PDF]

, 2017
Background and aims: Vascular disease is a common comorbidity in Parkinson’s disease patients. Statins are potentially neuroprotective for Parkinson’s disease through non-vascular mechanisms.
Cheng, Kelvin K.W., Grosset, Donald G., Grosset, Katherine A., Swallow, Diane M.A.   +3 more
core   +1 more source

Protein engineering to develop a redox insensitive endothelial nitric oxide synthase

Redox Biology, 2014
The zinc tetrathiolate (ZnS4) cluster is an important structural feature of endothelial nitric oxide synthase (eNOS). The cluster is located on the dimeric interface and four cysteine residues (C94 and C99 from two adjacent subunits) form a cluster with ...
Ruslan Rafikov, Sanjiv Kumar, Saurabh Aggarwal, Daniel Pardo, Fabio V. Fonseca, Jessica Ransom, Olga Rafikova, Qiumei Chen, Matthew L. Springer, Stephen M. Black   +9 more
doaj   +1 more source

Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial [PDF]

, 2019
Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage.
Al-Shahi Salman, Rustam, Baigent, Colin, Dennis, M S, Lasserson, Daniel, Murray, G D, Newby, D E, others,, Rajkumar, Chakravarthi, RESTART Collaboration,, Sandercock, P A G, Sprigg, N, Stephen, J, Sudlow, C L M, Wardlaw, J M, Werring, D J, White, P M, Whiteley, W N   +16 more
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Sex Differences in Stroke Subtypes, Severity, Risk Factors, and Outcomes Among Elderly Patients with Acute Ischemic Stroke

Frontiers in Aging Neuroscience, 2015
Background: Although the age-specific incidence and mortality of stroke is higher among men, stroke has a greater clinical effect on women. However, the sex differences in stroke among elderly patients are unknown.
Changshen eYu, Zhongping eAn, Wenjuan eZhao, Wanjun eWang, Chunlin eGao, Shoufeng eLiu, Jinghua eWang, Jialing eWu   +7 more
doaj   +1 more source

Vascular disease and vascular risk factors in relation to motor features and cognition in early Parkinson's disease [PDF]

, 2016
Funded by Parkinson's UK National Institute for Health Research (NIHR) DeNDRoN network NIHR Newcastle Biomedical Research Unit Newcastle University NIHR funded Biomedical Research Centre in CambridgePeer reviewedPublisher ...
Bajaj, Nin, Barker, Roger A, Ben-Shlomo, Yoav, Burn, David J, Grosset, Donald G, Grosset, Katherine A, Hardy, John, Lawton, Michael A, Malek, Naveed, Marrinan, Sarah L, Morris, Huw R, PRoBaND Clinical Consortium, Swallow, Diane M A, Williams, Nigel M, Wood, Nicholas   +14 more
core   +5 more sources

Long‐Term Outcomes of Patients With Mediastinal Radiation–Associated Severe Aortic Stenosis and Subsequent Surgical Aortic Valve Replacement: A Matched Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
Background Cardiac disease after mediastinal radiotherapy for thoracic malignancy (chest radiotherapy [XRT]) often manifests as progressive aortic stenosis. In patients with XRT‐induced severe aortic stenosis undergoing surgical aortic valve replacement (
Eoin Donnellan, Ahmad Masri, Douglas R. Johnston, Gosta B. Pettersson, L. Leonardo Rodriguez, Zoran B. Popovic, Eric E. Roselli, Nicholas G. Smedira, Lars G. Svensson, Brian P. Griffin, Milind Y. Desai   +10 more
doaj   +1 more source