Results 61 to 70 of about 11,970,410 (409)

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Rivaroxaban versus Enoxaparin in Patients with Radial Artery Occlusion after Transradial Coronary Catheterization: A Pilot Randomization Trial

open access: yesVascular Specialist International
The radial artery is currently the main vascular access site for cardiac catheterization. Radial artery occlusion (RAO), although a relatively silent complication, raises concerns because of its potential impact on future procedures.
Mohsen Maadani   +11 more
doaj   +1 more source

Kallikrein‐1 Blockade Inhibits Aortic Expansion in a Mouse Model and Reduces Prostaglandin E2 Secretion From Human Aortic Aneurysm Explants

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Abdominal aortic aneurysm (AAA) is an important cause of mortality in older adults. The kinin B2 receptor agonist, bradykinin, has been implicated in AAA pathogenesis through promoting inflammation.
Corey S. Moran   +5 more
doaj   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Electrochemical sclerotherapy with bleomycin for the treatment of low-flow vascular malformations: a comprehensive review

open access: yesVeins and Lymphatics
Low-Flow Vascular Malformations (LFVMs) are a diverse group of abnormal vascular lesions characterized by slow blood flow that can involve veins, capillaries, or lymphatic vessels.
Lorenzo Ciofani   +4 more
doaj   +1 more source

Fatty acid methyl esters as a potential therapy against cerebral ischemia

open access: yesOilseeds and fats, crops and lipids, 2016
Saturated fatty acids have been traditionally thought to be detrimental in circulation. However, we describe the beneficial effects of palmitic and stearic acid methyl esters as it relates to neuroprotection and cerebral vasodilatory properties in global
Hui-Chao Lee Reggie   +9 more
doaj   +1 more source

Cathepsin L Promotes Vascular Intimal Hyperplasia after Arterial Injury

open access: yesMolecular Medicine, 2017
The inflammatory pathways that drive the development of intimai hyperplasia (IH) following arterial injury are not fully understood. We hypothesized that the lysosomal cysteine protease cathepsin L activates processes leading to IH after arterial injury.
Jingjing Cai   +12 more
doaj   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Smoking, dementia and cognitive decline in the elderly, a systematic review. [PDF]

open access: yes, 2008
Background. Nicotine may aid reaction time, learning and memory, but smoking increases cardiovascular risk. Cardiovascular risk factors have been linked to increased risk of dementia.
Beckett, N   +5 more
core   +4 more sources

Progress in the Metabolomics of Acute Coronary Syndrome

open access: yesReviews in Cardiovascular Medicine, 2023
Acute coronary syndrome (ACS) is a severe type of coronary heart disease (CHD) with increasing prevalence and significant challenges for prevention and treatment.
Fu Zhang   +7 more
doaj   +1 more source

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