Results 211 to 220 of about 4,094,904 (310)

Fibrinogen-associated plasma metabolites and implications for coagulation, inflammation, and vascular diseases. [PDF]

J Thromb Haemost
Nicholas JC, Alkis T, Bis JC, Boerwinkle E, Brody JA, Clish CB, de Vries PS, Gao Y, Gerzsten RE, Guo X, Johnson AD, Larson MG, Lemaitre RN, Psaty BM, Vasan RS, Reiner AP, Rich SS, Rodriguez B, Rong J, Rotter JI, Simino J, Smith NL, Wilson J, Yao J, Morrison AC, Yu B, Raffield LM.   +26 more
europepmc   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Integrative functional genomics analysis identifies pleiotropic genes for vascular diseases. [PDF]

Nat Commun
Solomon CU, McVey DG, Andreadi C, Gong P, Turner L, Song DSS, Zhang H, Lee DP, Karamanavi E, Yang W, Chu J, Chen R, Haworth KE, Anene-Nzelu CG, Li H, Denniff MJ, Li PY, Zhang Y, Huang X, Morris GE, Greer PA, Stringer EJ, Yu H, Foo RSY, Douglas G, Samani NJ, Webb TR, Ye S.   +27 more
europepmc   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source

Therapeutic Targeting of the Bradykinin B2 Receptor in Immunological and Vascular Diseases: Insights from Kinin Biology to Clinical Outcomes. [PDF]

Clin Rev Allergy Immunol
Riedl MA, Cohn DM, Magerl M, Farkas H, Aygören-Pürsün E, Banerji A, Bernstein JA, Schmaier AH, Pardali E, Lesage A, Lu P, Newby DE.   +11 more
europepmc   +1 more source

Microfluidic Engineering of Microgels: A Review of Emerging Technologies, Materials, Fabrication Strategies, and Applications

Advanced Healthcare Materials, EarlyView.
Recent advances in microfluidic technologies for microgel fabrication are critically reviewed, highlighting the capabilities and limitations of major microfluidic platforms and discussing how platform design, material selection, and crosslinking strategies influence microgel architecture and functionality. Current challenges and future opportunities in
Afshin Abrishamkar, Laura Neely, Cynthia Pham, Nada Ibrahim, Alexis Larios‐Cervantes, Ben A. Kertesz, Todd Hoare   +6 more
wiley   +1 more source

Effect of sildenafil on resting and exercise haemodynamics in hypoxia in patients with pulmonary vascular diseases: data from a randomised controlled trial. [PDF]

ERJ Open Res
Lichtblau M, Schneider SR, Müller J, Bauer M, Carta AF, Mayer L, Schwarz EI, Furian M, Saxer S, Ulrich S.   +9 more
europepmc   +1 more source

Macrophage–Fibroblast Crosstalk Governs Tumor Mechanics, as Revealed by Spatiotemporal Force Mapping in 3D Spheroids

Advanced Healthcare Materials, EarlyView.
This study shows crosstalk among tumor cells, fibroblasts, and macrophages alters the physical forces inside 3D tumor spheroids. Incorporating deformable microparticles in 3D tumor spheroids, the researchers mapped mechanical stresses spatially and with respect to tumor growth (temporally).
Kunal P. Pednekar, Daan Vorselen, Jai Prakash   +2 more
wiley   +1 more source

Ferroptosis of smooth muscle cells in vascular diseases: from basic principles to clinical translation. [PDF]

Cell Death Discov
Yang Y, Nawabi AQ, Yao Y, Liu N.
europepmc   +1 more source