Results 1 to 10 of about 783,911 (258)

Obesity and Endothelial Function

Biomedicines, 2022
Obesity is a major public health problem and is related to increasing rates of cardiovascular morbidity and mortality. Over 1.9 billion adults are overweight or obese worldwide and the prevalence of obesity is increasing.
Masato Kajikawa, Yukihito Higashi
doaj   +3 more sources

Endothelial Function in Dyslipidemia: Roles of LDL-Cholesterol, HDL-Cholesterol and Triglycerides

Cells, 2023
Dyslipidemia is associated with endothelial dysfunction. Endothelial dysfunction is the initial step for atherosclerosis, resulting in cardiovascular complications.
Yukihito Higashi
doaj   +3 more sources

Endothelial-erythrocyte glycocalyx exchange enables liquid biopsies of endothelial function [PDF]

Nature Communications
The luminal surface of blood vessels is covered by a hydrated mesh of sugars and proteins termed the endothelial glycocalyx. The glycocalyx forms a permeability barrier and helps regulate leucocyte migration.
Matthew J. Butler, Raina R. Ramnath, Michael Crompton, Jasmine Aldam, Monica Gamez, Colin Down, Charley Heffer, Chris Neal, Jialu Li, Yan Qiu, Laura Carey, Laura Skinner, Stephen Cross, Yamaguchi Yu, Judit Sutak, Victoria Bills, Gavin I. Welsh, Rebecca R. Foster, Simon C. Satchell   +18 more
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Vascular Endothelial Function in Periodontal Disease: Role of Inflammation [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Periodontal disease is a chronic inflammatory condition of the periodontal tissues, encompassing pathologies such as gingivitis and periodontitis. It has been shown that these conditions not only lead to localized inflammation but also have systemic ...
Yukihito Higashi, Akira Taguchi
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Exercise-Generated β-Aminoisobutyric Acid (BAIBA) Reduces Cardiomyocyte Metabolic Stress and Apoptosis Caused by Mitochondrial Dysfunction Through the miR-208b/AMPK Pathway

Frontiers in Cardiovascular Medicine, 2022
ObjectiveTo explore the cardioprotective effects of exercise-derived β-aminoisobutyric (BAIBA) on cardiomyocyte apoptosis and energy metabolism in a rat model of heart failure (HF).MethodsIn male Sprague-Dawley rats (8-week-old), myocardial infarction ...
Yanan Yu, Yanan Yu, Wewei Chen, Wewei Chen, Ming Yu, Ming Yu, Jinsha Liu, Jinsha Liu, Huan Sun, Huan Sun, Ping Yang, Ping Yang   +11 more
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Photophysical Details and O2-Sensing Analysis of a Eu(III) Complex in Polymer Composite Nanofibers Prepared by Electrospinning

Frontiers in Chemistry, 2022
An as-synthesized Eu(III) complex, denoted as Eu(N-DPNQ)(TTD)3, was prepared and characterized, and the antenna mechanism between these ligands and central metal emitter was studied.
Chunguo Cui, Lina Song, Chao Li, Tiantian Lin, Kaiyao Shi   +4 more
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Trace Elements Open a New Direction for the Diagnosis of Atherosclerosis

Reviews in Cardiovascular Medicine, 2023
Abnormal or excessive accumulation of adipose tissue leads to a condition called obesity. Long-term positive energy balance arises when energy intake surpasses energy expenditure, which increases the risk of metabolic and other chronic diseases, such as ...
Heyu Meng, Jianjun Ruan, Yanqiu Chen, Zhaohan Yan, Jinsha Liu, Xue Wang, Xin Meng, Jingru Wang, Qiang Zhang, Xiangdong Li, Fanbo Meng   +10 more
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Association of Low Expression of NUMB in Peripheral Blood with Acute Myocardial Infarction

Cardiology Research and Practice, 2022
Objective. Our study’s goal was to find out acute myocardial infarction (AMI) patients’ NUMB gene expression patterns and to evaluate its role as a diagnostic marker for AMI detection. Methods.
Heyu Meng, Lihong Li, Jianjun Ruan, Yanqiu Chen, Zhaohan Yan, Jinsha Liu, Xiangdong Li, Cuiying Mao, Ping Yang   +8 more
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Advancements in the Regulation of Different-Intensity Exercise Interventions on Arterial Endothelial Function

Reviews in Cardiovascular Medicine, 2023
Normal-functioning endothelium is crucial to maintaining vascular homeostasis and inhibiting the development and progression of cardiovascular diseases such as atherosclerosis.
Qian-Qian Li, Kai-Rong Qin, Wen Zhang, Xiu-Mei Guan, Min Cheng, Yan-Xia Wang   +5 more
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Serum Zinc Ion Concentration Associated with Coronary Heart Disease: A Systematic Review and Meta-Analysis

Cardiology Research and Practice, 2022
Aim. Coronary heart disease is a major cause of mortality in developed and developing countries. Changes in the trace element concentration in the human body are one of the main reasons for the transition of the human body from a healthy to a diseased ...
Heyu Meng, Jianjun Ruan, Yanqiu Chen, Zhaohan Yan, Xin Meng, Xiangdong Li, Jinsha Liu, Cuiying Mao, Ping Yang   +8 more
doaj   +1 more source