Results 31 to 40 of about 783,911 (258)
Frontiers in Endocrinology, 2021 To assess the variations in pulmonary function and vascular endothelial function in their early stages (without related complications). A total of 162 type 2 diabetes mellitus (T2DM) patients without diabetes complications and 55 healthy people were ...
He Tai +11 more
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Journal of Pharmacological Sciences, 2003 : Evidence has accumulated that impairment of vascular endothelial function is the initial step in the development of atherosclerosis. One important finding is impairment of the release of endothelium-dependent relaxing factor, which is now thought to be
Masayoshi Hashimoto +3 more
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The endothelial αENaC contributes to vascular endothelial function in vivo. [PDF]
PLoS ONE, 2017 The Epithelial Sodium Channel (ENaC) is a key player in renal sodium homeostasis. The expression of α β γ ENaC subunits has also been described in the endothelium and vascular smooth muscle, suggesting a role in vascular function.
Antoine Tarjus +9 more
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The role of HDAC2 inhibition in cardioprotection against doxorubicin-induced myocardial injury
Frontiers in Cardiovascular MedicineIntroductionThe molecular mechanisms underlying cardioprotection against doxorubicin (DOX)-induced myocardial injury are poorly understood. Histone deacetylase 2 (HDAC2) plays a significant role in oxidative stress, apoptosis, and mitochondrial ...
Jinsha Liu +7 more
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Endothelial connexins in vascular function
Vascular Biology, 2019 Gap junctions are essential for intercellular crosstalk in blood and lymphatic vasculature. These clusters of intercellular channels ensure direct communication among endothelial cells and between endothelial and smooth muscle cells, and the ...
Aurélie Hautefort +2 more
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Pelvic hematoma: The same complication with different etiology after patent foramen ovale closure
HeliyonWell-known complication associated with patent foramen ovale (PFO) closure include infection, acute cardiac tamponade, and local complications such as adjacent arterial or nerve damage, hemorrhage, and thrombophlebitis.
Guohui Liu +4 more
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Imaging Assessment of Endothelial Function: An Index of Cardiovascular Health
Frontiers in Cardiovascular Medicine, 2022 Endothelial dysfunction is a key early mechanism in a variety of cardiovascular diseases and can be observed in larger conduit arteries as well as smaller resistance vessels (microvascular dysfunction). The presence of endothelial dysfunction is a strong
Anum S. Minhas +8 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
RHEUMATIC DISEASES AND ENDOTHELIAL FUNCTION
Вопросы современной педиатрии, 2018 The review analyzes the role of chronic inflammatory diseases in the induction of endothelial dysfunction as a factor in the acceleration of atherosclerotic changes in the cardiovascular system.
Varvara L. Мarchuk +2 more
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