Results 51 to 60 of about 797,667 (303)

Influence of hyperhomocysteinemia on the cellular redox state - Impact on homocysteine-induced endothelial dysfunction [PDF]

, 2003
Hyperhomocysteinemia is an independent risk factor for the development of atherosclerosis. An increasing body of evidence has implicated oxidative stress as being contributory to homocysteines deleterious effects on the vasculature.
Keaney, John F., Weiss, Norbert, Postea, Otilia, Heydrick, Stanley J., Keller, Christiane, Loscalzo, Joseph   +5 more
core   +1 more source

RHEUMATIC DISEASES AND ENDOTHELIAL FUNCTION

Вопросы современной педиатрии, 2018
The review analyzes the role of chronic inflammatory diseases in the induction of endothelial dysfunction as a factor in the acceleration of atherosclerotic changes in the cardiovascular system.
Varvara L. Мarchuk, Nickolai V. Sobotyuk, Sergei V. Bochantsev   +2 more
doaj   +1 more source

Effectiveness of a Novel Low‐Density Lipoprotein Apheresis Device Rheocarna in Patients Undergoing Hemodialysis With Chronic Limb‐Threatening Ischemia: A Single‐Center Retrospective Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic limb‐threatening ischemia (CLTI) is a severe form of lower‐extremity artery disease characterized by distal lesions and microcirculatory impairment, limiting revascularization efficacy. Rheocarna is a direct hemoperfusion low‐density lipoprotein (LDL) adsorption device with potential rheological and anti‐inflammatory ...
Kunihiro Ishioka, Takayasu Ohtake, Kei Ohmori, Chika Shibuya, Tomoki Tsukahara, Mizuki Yamano, Yasuhiro Mochida, Machiko Oka, Kyoko Maesato, Yusuke Tsukamoto, Hidekazu Moriya, Sumi Hidaka, Shuzo Kobayashi   +12 more
wiley   +1 more source

Angiotensin II impairs endothelial function via tyrosine phosphorylation of the endothelial nitric oxide synthase

, 2009
Proline-rich tyrosine kinase 2 (PYK2) can be activated by angiotensin II (Ang II) and reactive oxygen species. We report that in endothelial cells, Ang II enhances the tyrosine phosphorylation of endothelial NO synthase (eNOS) in an AT1-, H2O2-, and PYK2-
Loot, Annemarieke E., Ingrid Fleming, Annemarieke E. Loot, Fißlthaler, Beate, Fleming, Ingrid, Judith G. Schreiber, Beate Fisslthaler, Schreiber, Judith G.   +7 more
core   +1 more source

Flow mediated dilation in patient with Berlin Heart Incor left ventricle assist device

Monaldi Archives for Chest Disease, 2016
Endothelial function measured with brachial ultrasound (BU) is a validated prognostic factor in heart failure patients. LVAD (left ventricle assist device) application is a promising surgical technique to treat refractory heart failure patients both as a
Franco Tarro Genta, Elena Colajanni, Pierluigi Sbarra, Massimo Tidu, Mauro Rinaldi, Enzo Bosimini   +5 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Glu298Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function

, 2002
An endothelial nitric oxide synthase (eNOS) gene polymorphism (Glu298Asp) has been associated with cardiovascular disease. We investigated whether carriage of the polymorphism was associated with functional changes in the endothelium, and how genotype ...
Jeerooburkhan, N., Muller, D.P.R., Mullen, M.J., Deanfield, J.E., Muller, DP, Deanfield, JE, Humphries, SE, Kattenhorn, M., Cole, T.J., Lucas, A, Humphries, S.E., Leeson, Christopher, Kattenhorn, M, Hingorani, AD, Jeerooburkhan, N, Hingorani, S.D., Leeson, CP, Mullen, MJ, Leeson, C.P.M., Cole, TJ, Lucas, A.   +20 more
core   +1 more source

Effects of prior moderate exercise on postprandial metabolism and vascular function in lean and centrally obese men [PDF]

, 2004
Objectives: We investigated whether a session of prior exercise could ameliorate postprandial endothelial dysfunction. Background: Endothelial function is impaired after fat ingestion, and this may be related to rises in triglyceride concentrations.
John R. Petrie, Stephen J. Cleland, Petrie, J.R., Sattar, N., William R. Ferrell, Cleland, Stephen J., Caslake, Muriel J., Gill, Jason M.R., Jason M.R. Gill, Muriel J. Caslake, Packard, C.J., Petrie, John, Ali Al-Mamari, Sattar, Naveed, Gill, J.M.R., Ferrell, William R., Petrie, John R., Al-Mamari, A., Caslake, M.J., Naveed Sattar, Cleland, S.J., Chris J. Packard, Ferrell, W.R., Al-Mamari, Ali, Packard, Chris J.   +24 more
core   +1 more source

Low expression of Notch1 may be associated with acute myocardial infarction

Frontiers in Cardiovascular Medicine
BackgroundThe transmembrane protein Notch1 is associated with cell growth, development, differentiation, proliferation, apoptosis, adhesion, and the epithelial mesenchymal transition.
Qing Zhang, Qing Zhang, Qing Zhang, Qing Zhang, Heyu Meng, Heyu Meng, Heyu Meng, Heyu Meng, Xue Wang, Xue Wang, Xue Wang, Xue Wang, Yanqiu Chen, Yanqiu Chen, Yanqiu Chen, Yanqiu Chen, Zhaohan Yan, Zhaohan Yan, Zhaohan Yan, Zhaohan Yan, Jianjun Ruan, Jianjun Ruan, Jianjun Ruan, Jianjun Ruan, Fanbo Meng, Fanbo Meng, Fanbo Meng, Fanbo Meng   +27 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source