Results 61 to 70 of about 797,667 (303)
, 2001 Background: Low birth weight is related to increased risk of coronary heart disease in adults and recently has been associated with vascular endothelial dysfunction in children.
Leeson, Christopher +10 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Molecular mechanisms and modulation of Endothelial Progenitor Cell function in South Asian men [PDF]
, 2012 South Asian ethnicity has long been considered a contributory factor in the development of atherosclerosis and cardiovascular disease. Endothelial dysfunction is considered to be the precursor of atherosclerosis, and South Asian ethnicity has been linked
Baliga, Vivek
core
Comparison between Fenugreek and Lovastatin in restoration of endothelial function in an experimental old rat model [PDF]
Acta Medica Iranica, 2003 The aim of this study was to compare the effectiveness of Fenugreek (Trigonella foenum-graecum) with that of lovastatin in restoration of endothelia function in the aorta taken form aged N-Mair rats.
"Pipelzadeh MH +3 more
doaj +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Endothelial function in normal and pathological conditions
Медицинский совет, 2019 The article presents the data on the state of endothelial function in the normally and in various diseases and conditions. The basic functions of endothelium in modulation of vascular tone, atrombogenicity and thrombogenicity of the vascular wall ...
A. V. Pizov +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Scientific Reports, 2020 Only a few reports have examined vascular endothelial function before and after educational hospitalization and the factors that affect it in patients with type 2 diabetes mellitus (T2DM). The aim of this study was to assess vascular endothelial function
Yukiko Goshima +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Heparinase selectively sheds heparan sulphate from the endothelial glycocalyx [PDF]
, 2008 A healthy vascular endothelium is coated by the endothelial glycocalyx. Its main constituents are transmembrane syndecans and bound heparan sulphates. This structure maintains the physiological endothelial permeability barrier and prevents leukocyte and ...
Rehm, Markus +6 more
core +1 more source