Results 241 to 250 of about 1,768,847 (310)

A New 3D Colon on a Chip to Decipher the Influence of Mechanical Forces on the Physiological Cellular Ecosystem

Advanced Healthcare Materials, EarlyView.
To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery, Lauriane Gérémie, Julie Brun, Lucas Chassatte, Giacomo Gropplero, Réda Bouras, Jieun Choo, Bertrand Cinquin, Alba Marcellan, Danijela Matic Vignjevic, Stéphanie Descroix   +10 more
wiley   +1 more source

Suprachoroidal Delivery of Viral and Nonviral Vectors for Treatment of Retinal and Choroidal Vascular Diseases. [PDF]

Am J Ophthalmol
Lim Y, Campochiaro PA, Green JJ.
europepmc   +1 more source

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

Advanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan, Jose Yeste, Mar Alvarez, Denise Marrero, Laura Casado‐Medina, Yvonne Richaud‐Patin, Olalla García‐Iglesias, Jagoda Litowczenko, Alba Morillas Garcia, Anton Guimerà, Xavi Illa, Rosa Villa, Angel Raya   +12 more
wiley   +1 more source

Pulmonary vascular diseases at high altitude - is it safe to live in the mountains? [PDF]

Curr Opin Pulm Med
Titz A, Hoyos R, Ulrich S.
europepmc   +1 more source

The role of m6A in angiogenesis and vascular diseases. [PDF]

iScience
Chen K, Li WD, Li XQ.
europepmc   +1 more source

The role of pericyte in ocular vascular diseases. [PDF]

J Biomed Res
Shi L, Ge H, Ye F, Li X, Jiang Q.
europepmc   +1 more source

Targeting SLC25A33 Suppresses Vascular Smooth Muscle Cell Proliferation and Migration by Reducing Cytosolic mtDNA Levels: Implications for Occlusive Vascular Diseases. [PDF]

Diabetes Metab J
Kim D, Shin J, Choi YK, Lee YM, Park KG, Kim HS, Byun JK.   +6 more
europepmc   +1 more source

The Role and Mechanism of Vascular Aging in Geriatric Vascular Diseases. [PDF]

Aging Dis
Zhang S, Xia B, Kalionis B, Li H, Zhang X, Zhang X, Xia S.   +6 more
europepmc   +1 more source

A simplified in vitro disease-mimicking culture system can determine the angiogenic effect of medicines on vascular diseases. [PDF]

Cytotechnology
Moon S, Ito Y.
europepmc   +1 more source