Results 271 to 280 of about 10,748,261 (341)

RBC Membrane‐Camouflaged Nanosystem‐Mediated Synergistic Drug Combination for Enhanced Anti‐Tumor Therapy

Advanced Healthcare Materials, EarlyView.
An RBC membrane camouflaged, cell‐penetrating peptides R8‐based drug delivery system is constructed to achieve a synergistic combination of natural compounds triptolide (TP) and celastrol (Cel), inducing tumor cell apoptosis, reducing tumor metastasis invasion and triggering autophagy disorder in breast cancer and liver cancer.
Qian Cheng, Xuemei Zhong, Lu Deng, Xinling He, Miaoxizi Luo, Ruibing Wang, Jinming Zhang   +6 more
wiley   +1 more source

PDE4 inhibitors: potential protective effects in inflammation and vascular diseases. [PDF]

Front Pharmacol
Fan T, Wang W, Wang Y, Zeng M, Liu Y, Zhu S, Yang L.   +6 more
europepmc   +1 more source

Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis

Advanced Healthcare Materials, EarlyView.
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han, Weiping Lin, Yuanxiong Cao, Patricia Murray, Bettina Wilm, Stephen J McWilliam, Jude Curran, Ruoxiao Xie   +7 more
wiley   +1 more source

Targeting PDGF/PDGFR Signaling Pathway by microRNA, lncRNA, and circRNA for Therapy of Vascular Diseases: A Narrow Review. [PDF]

Biomolecules
Ma CN, Shi SR, Zhang XY, Xin GS, Zou X, Li WL, Guo SD.   +6 more
europepmc   +1 more source

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

Advanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla, Vincenzo Verdi, Willemijn de Voogt, Mariona Estapé Sentí, Arnold C. Koekman, Julian Rietveld, Sven van Kempen, Qiangbing Yang, Juliette van Merris, Guido Jenster, Martin E. van Royen, Marcel H. Fens, Sander A. A. Kooijmans, Wytske M. van Weerden, Guillaume van Niel, Pieter Vader, Raymond M. Schiffelers   +16 more
wiley   +1 more source

An Association between HTRA1 and TGF-β₂ in the Vitreous Humor of Patients with Chorioretinal Vascular Diseases. [PDF]

J Clin Med
Fukushima Y, Takahashi S, Nakamura M, Inoue T, Fujieda Y, Sato T, Noguchi S, Tsujikawa M, Sakaguchi H, Nishida K.   +9 more
europepmc   +1 more source

S11. The Rehabilitation of the Patients with Cerebro-Vascular Diseases

, 1963
S Katsuki, Yoshigoro Kuroiwa, Tsunoru Miyazaki, Motohiro Kato   +3 more
openalex   +2 more sources

Biomimetic, Suturable, and Extensible Electrospun Scaffolds for Lower Urinary Tract Surgical Reconstruction

Advanced Healthcare Materials, EarlyView.
Biomimetic, suturable, biodegradable fibrous scaffolds are engineered to mimic the tensile properties of LUT tissue using photocrosslinked 5:5% weight per volume elastin‐like peptide and methacrylated gelatin (5E5G). In vitro, urothelium, smooth muscle, and fibroblast 7 day cytocompatibility is demonstrated.
Renea M. Sturm, Yadi Huo, Felix Yiu, Yimin Gu, Ronak Afshari, Zijian Zhong, Ruby Jimenez, Rebekah Jung, Aljohn Cabuan, Keshav Shukla, Karen Harrison, Judy Su, George E. Aninwene II, Victoria Lee, Mahsa Ghovvati, Kaavian Shariati, Nicholas Jackson, Song Li, Nasim Annabi   +18 more
wiley   +1 more source

An Emerging Role of Micro- and Nanoplastics in Vascular Diseases. [PDF]

Life (Basel)
Lee SE, Yoon HK, Kim DY, Jeong TS, Park YS.   +4 more
europepmc   +1 more source