Results 91 to 100 of about 172,930 (297)

Reduced CD40L expression on ex vivo activated CD4+T-lymphocytes from patients with excellent renal allograft function measured with a rapid whole blood flow cytometry procedure [PDF]

, 2004
Background: The CD40-CD40L (CD154) costimulatory pathway plays a critical role in the pathogenesis of kidney allograft rejection. In renal transplant biopsies, CD4+ CD40L+ graft-infiltrating cells were detected during chronic rejection in contrast to ...
Lederer, Stephan R., Sitter, Thomas, Toepfer, Marcel, Gruber, R., Landgraf, R., Friedrich, N.   +5 more
core   +1 more source

Lateral Femoral Circumflex Arterial System as Donor Vessels for Extremity Replantation

Journal of Reconstructive Microsurgery Open, 2016
Background Forearm replantation presents with many challenges, including the need for vascular graft material for revascularization. Although frequently harvested for vascular reconstruction, the saphenous vein is often suboptimal for use as vascular ...
Erin M. Taylor, Matthew L. Iorio
doaj   +1 more source

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

Advanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones, Madeline Laude, Zeenat Oyebanji, Ruchi Birur, Andres Luengo Martinez, Isabelle Gilbert, Phillip Baek, Nichole Longbottom, Nicole McCullough, Staci J. Horn, Chien‐Yu Lin, Matthew J. Lohr, Fred Clubb, Manuel K. Rausch, Elizabeth Cosgriff‐Hernandez   +14 more
wiley   +1 more source

New Graft for Low Friction Tunneling in Vascular Access Surgery

, 2004
Purpose Prosthetic accesses of the upper extremity have been in use for more than 25 years. Many different conduits have been employed; investigators have continually searched for a graft with superior properties.
J. Livingstone, Raines, J.K., Schild, A.F., K. Alfieri, J.K. Raines, Livingstone, J., A.F. Schild, Alfieri, K., Baltodano, N.M., N.M. Baltodano   +9 more
core   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Newly Designed Compliant Hierarchic Hybrid Vascular Grafts Wrapped with a Microprocessed Elastomeric Film—I: Fabrication Procedure and Compliance Matching

Cell Transplantation, 2002
The object of this study was to develop a compliant hybrid vascular graft minimally supported by an elastomeric scaffold for arterial replacement. The hybrid vascular grafts designed were composed of three layers: an inner surface lined with endothelial ...
Takehisa Matsuda, Hongbing He
doaj   +1 more source

Rapid Endothelialization of Off-the-Shelf Small Diameter Silk Vascular Grafts

JACC: Basic to Translational Science, 2018
Synthetic vascular grafts for small diameter revascularization are lacking. Clinically available conduits expanded polytetrafluorethylene and Dacron fail acutely due to thrombosis and in the longer term from neointimal hyperplasia.
Elysse C. Filipe, MSc, Miguel Santos, MSc, Juichien Hung, MSc, Bob S.L. Lee, MSc, Nianji Yang, MPhil, Alex H.P. Chan, BSc, Martin K.C. Ng, MD, PhD, Jelena Rnjak-Kovacina, PhD, Steven G. Wise, PhD   +8 more
doaj   +1 more source

Coaxially Electrospun Myocardial dECM‐ Based Nanofibrous Scaffolds Demonstrate Enhanced Cardiomyocyte Biocompatibility

Advanced Healthcare Materials, EarlyView.
Our coaxial electrospinning system is capable of incorporating decellularized myocardial extracellular matrix in a core‐sheath configuration, creating nanofibrous scaffolds. These scaffolds, in turn, support the maintenance of functional cardiomyocytes adhered to the surface of these bioactive scaffolds.
Dhanusha N. Rajapakse, Mahtab Khodadadi, Kiran M. Ali, Suh Hee Cook, Bryson T. Proctor, Tanya Upadhyay, Daxian Zha, Fatema Tuj Jahura, Marziyeh Boosaliki, Jessica M. Gluck   +9 more
wiley   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source

Aortic Arch Redo Surgery for Endograft Migration and Premature Thrombosis of Debranching Graft

The Thoracic & Cardiovascular Surgeon Reports, 2013
Background Thoracic endovascular aortic repair (TEVAR) has become the treatment of choice in the management of the aortic arch and descending aorta diseases.
Yihua Liu, Pablo Maureira, Thiery Folliguet, Jean-Pierre Villemot   +3 more
doaj   +1 more source