Results 111 to 120 of about 2,140,459 (401)

Rapid Endothelialization of Off-the-Shelf Small Diameter Silk Vascular Grafts

JACC: Basic to Translational Science, 2018
Synthetic vascular grafts for small diameter revascularization are lacking. Clinically available conduits expanded polytetrafluorethylene and Dacron fail acutely due to thrombosis and in the longer term from neointimal hyperplasia.
Elysse C. Filipe, MSc, Miguel Santos, MSc, Juichien Hung, MSc, Bob S.L. Lee, MSc, Nianji Yang, MPhil, Alex H.P. Chan, BSc, Martin K.C. Ng, MD, PhD, Jelena Rnjak-Kovacina, PhD, Steven G. Wise, PhD   +8 more
doaj   +1 more source

Role of noncoding RNA in vascular remodelling [PDF]

, 2016
Purpose of review: Noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) are becoming fundamentally important in the pathophysiology relating to injury-induced vascular remodelling.
Baker, Andrew H., Bradshaw, Angela C., Deng, Lin   +2 more
core   +1 more source

Preliminary In Vivo Evaluation of a Hybrid Armored Vascular Graft Combining Electrospinning and Additive Manufacturing Techniques

Drug Target Insights, 2016
In this study, we tested in vivo effectiveness of a previously developed poly-L-lactide/poly-8-caprolactone armored vascular graft releasing heparin. This bioprosthesis was designed in order to overcome the main drawbacks of tissue-engineered vascular ...
C. Spadaccio, F. Nappi, F. De Marco, P. Sedati, Fraser Sutherland, M. Chello, M. Trombetta, A. Rainer   +7 more
semanticscholar   +1 more source

Tailoring the Properties of Functional Materials With N‐Oxides

Advanced Functional Materials, EarlyView.
The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich, Michelle Kobus, Shirin Mesgarha, Erica Moretto, Laurens Grosche, Wolfgang Maison   +5 more
wiley   +1 more source

Bioinspired Bromination Enables Extensible, Strain‐Stiffening Resilin Peptide Scaffolds with Tunable Degradation

Advanced Functional Materials, EarlyView.
Bioinspired bromination of a resilin‐derived peptide enables the fabrication of electrospun nanofibrous scaffolds that uniquely combine strain‐stiffening elasticity, proteolytic stability, and antioxidant functionality. These brominated peptide–gelatin hybrids mimic the extensibility of natural elastomers, demonstrating tunable mechanical resilience ...
Elisa Marelli, Lorenzo Sori, Chiara Russo, Claudia Pigliacelli, Lorenza Draghi, Monica Soncini, Pierangelo Metrangolo   +6 more
wiley   +1 more source

Aortic Arch Redo Surgery for Endograft Migration and Premature Thrombosis of Debranching Graft

The Thoracic & Cardiovascular Surgeon Reports, 2013
Background Thoracic endovascular aortic repair (TEVAR) has become the treatment of choice in the management of the aortic arch and descending aorta diseases.
Yihua Liu, Pablo Maureira, Thiery Folliguet, Jean-Pierre Villemot   +3 more
doaj   +1 more source

Transcriptome dynamics at Arabidopsis graft junctions reveal an intertissue recognition mechanism that activates vascular regeneration

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance Plant grafting is an ancient and agriculturally important technique. Despite its widespread use, little is known about how plants graft. Here, we perform a genome-wide transcriptome analysis of tissues above and below graft junctions.
Charles W. Melnyk, A. Gabel, Thomas J. Hardcastle, Sarah Robinson, Shunsuke Miyashima, I. Grosse, E. Meyerowitz   +6 more
semanticscholar   +1 more source

Generating Cell Surface Nucleated Hydrogels with an Artificial Membrane‐Binding Transglutaminase

Advanced Functional Materials, EarlyView.
Cell‐based therapies require advanced strategies to enhance cell delivery and bioactivity. Cell membrane engineering offers an avenue to impart new functions to delivered cells to boost their viability and function. Here, an artificial membrane‐binding transglutaminase is generated and biophysically characterized.
Rosalia Cuahtecontzi Delint, Tao Li, Kapil D. Patel, Will H. Zhang, Ben M. Carter, Graham J. Day, Adam W. Perriman   +6 more
wiley   +1 more source

Assessment of a novel, capsid-modified adenovirus with an improved vascular gene transfer profile [PDF]

, 2013
<p>Background: Cardiovascular disorders, including coronary artery bypass graft failure and in-stent restenosis remain significant opportunities for the advancement of novel therapeutics that target neointimal hyperplasia, a characteristic of both ...
AA Soyombo, AC Bradshaw, AC Bradshaw, AF Merrick, AH Baker, AL Parker, AL Parker, Alan L Parker, Andrew H Baker, Angela C Bradshaw, Audrey F Wright, B Vigl, C-C Liang, Christian Delles, DM Roberts, F Sakurai, F Vigant, K Doronin, Katie M White, KD Newman, M Hedman, M Hedman, M Jessup, MC Sprangers, MD Rekhter, MJE Havenga, MM Zanone, MO Hilutnen, N Inoue, O Kalyuzhniy, P Lemarchand, R Alba, R Alba, R Vogels, Raul Alba, RD Lopes, Robert A McDonald, RR Bradley, S Ishii, S Kuriyama, SA Nicklin, SD Carson, SJ George, SJ George, SM Sumida, SN Waddington, TD Henry, TW Johnson   +47 more
core   +2 more sources

Shape‐Morphing Nanoengineered Hydrogel Ribbons as Hemostats

Advanced Functional Materials, EarlyView.
This study introduces a self‐assembling, shape‐morphing nanoengineered hydrogel ribbon system that rapidly forms porous aggregates in situ for efficient hemostasis in trauma and surgical applications. Abstract Rapid and effective hemorrhage control remains a major challenge in trauma and surgical care, particularly for complex or noncompressible wounds.
Ryan Davis Jr, Saptarshi Biswas, Jacob Aragon, Asaf Dana, Jasmine Sureka, Vaaridhi Ramanuja, Jeevika Thazhaiselvam, Sarah E. Miller, Taylor H. Ware, Akhilesh K. Gaharwar   +9 more
wiley   +1 more source