Results 121 to 130 of about 883,493 (257)

Synchronous off-pump Coronary Bypass and Extra-anatomic Thoracic Aortobifemoral Graft Using Anterolateral Thoracotomy Single-center Experience

open access: yesIndian Journal of Vascular and Endovascular Surgery
Background: Aortoiliac occlusive disease can coexist with coronary artery disease in many instances leading to the dilemma of which problem to address first as for these patients with multiple comorbidities and high surgical risk, it is critical to ...
Apurva Shah   +3 more
doaj   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

open access: yesAdvanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert   +8 more
wiley   +1 more source

The Biomechanical Performance of Natural and Synthetic Polymers in Vascular Surgery: A Systematic Review

open access: yesProceedings
In vascular surgery, polymer materials, both natural and synthetic, are widely used for grafting, stenting, and tissue engineering [...]
Elnaz Abedini, Nima Feizlou
doaj   +1 more source

Angiogenesis-dependent and independent phases of intimal hyperplasia. [PDF]

open access: yes, 2004
BACKGROUND: Neointimal vascular smooth muscle cell (VSMC) proliferation is a primary cause of occlusive vascular disease, including atherosclerosis, restenosis after percutaneous interventions, and bypass graft stenosis. Angiogenesis is implicated in the
De Muinck, E   +9 more
core  

A BSCB‐Penetrating Nanoplatform for Enhanced Luteolin Delivery in PRMT2‐Targeted Epigenetic Therapy of Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
In this work, MSN‐BO@LUT penetrates the blood‐spinal cord barrier for luteolin delivery in spinal cord injury. The nanodrug suppresses neuroinflammation and promotes functional recovery of the spinal cord. Mechanistically, luteolin targets protein arginine N‐methyltransferase (PRMT2) to decrease toll‐like receptor 4 (TLR4) methylation, thereby ...
Yixuan Wang   +11 more
wiley   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

open access: yesAdvanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu   +5 more
wiley   +1 more source

Very small-diameter polyurethane vascular prostheses with rapid endothelialization for coronary artery bypass grafting

open access: yes, 1992
The growing, incidence of "redo" coronary artery bypass grafting (CABG) calls for the development of satisfactory prosthetic substitutes for the internal mammary artery or the saphenous vein.
M Goddard   +3 more
core  

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

open access: yesAdvanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li   +7 more
wiley   +1 more source

Vascular Reconstruction Is Not Warranted in Most Civilian Traumatic Shank Vascular Injuries

open access: yes, 2016
Operative management of traumatic shank vascular injuries (SVI) evolved significantly in the past few decades, thereby leading to a dramatic decrease in amputation rates.
Pizano, Louis R   +5 more
core   +1 more source

Restoring Endothelial Mitochondrial Homeostasis With a Bioactive Nanoshield Promotes Vascular Regeneration on Cardiovascular Implants

open access: yesAdvanced Science, EarlyView.
A bioactive poly(citrate‐polyglycol‐procyanidin) (PCGP) nanoshield is developed for cardiovascular implants to restore endothelial mitochondrial homeostasis following vascular injury. By preserving mitochondrial integrity, re‐establishing metabolic balance, and activating PI3K/Akt/eNOS‐NO signaling, the PCGP interface promotes functional endothelial ...
Xiyu Liu   +14 more
wiley   +1 more source

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