Results 61 to 70 of about 46,051 (295)

Genes and primary headaches: discovering new potential therapeutic targets [PDF]

, 2013
Genetic studies have clearly shown that primary headaches (migraine, tension-type headache and cluster headache) are multifactorial disorders characterized by a complex interaction between different genes and environmental factors.
Innocenzo Rainero, Koen Paemeleire, Alessandro Vacca, Elisa Rubino, Sarchielli, Paola, Vacca, Alessandro, Paemeleire, Koen, Gentile, Salvatore, Rainero, Innocenzo, De Martino, Paola, Salvatore Gentile, Lorenzo Pinessi, Gai, Annalisa, Annalisa Gai, Paola Sarchielli, Rubino, Elisa, Paola De Martino, Pinessi, Lorenzo   +17 more
core   +1 more source

Clinical Outcomes and Patient Experiences With Celiprolol Therapy in Vascular Ehlers–Danlos Syndrome: The First Non‐European Cohort

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Vascular Ehlers–Danlos syndrome (vEDS) is a hereditary connective tissue disorder caused by heterozygous pathogenic variants in COL3A1. European studies have shown that celiprolol may reduce the risk of life‐threatening vascular events, but outcomes in non‐European populations and the therapy's psychological impact remain unclear. We conducted
Megumi Furuhata‐Yoshimura, Tomomi Yamaguchi, Tomoki Kosho   +2 more
wiley   +1 more source

Clinical Reasoning Behind Non-Pharmacological Interventions for the Management of Headaches: A Narrative Literature Review [PDF]

, 2020
Headache is the clinical syndrome most commonly observed by neurologists in daily practice. Pharmacological and non-pharmacological treatments are commonly used for the management of headaches; however, the clinical reasoning behind these interventions ...
Plaza Manzano, Gustavo, Arias-Buría, José L, Florencio, Lidiane L, Gustavo Plaza-Manzano, César Fernández-de-las-Peñas, José L. Arias-Buría, Lidiane L. Florencio, Fernández-de-las-Peñas, César, Arias-Buría, José L., Plaza-Manzano, Gustavo, Florencio, Lidiane L.   +10 more
core   +2 more sources

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen, Kristin Ørstavik, Unni Steen, Mathias Toft, Cathrine Brunborg, Lena Lande Wekre   +5 more
wiley   +1 more source

Migraine-like headaches: a systematic review of secondary etiologies, clinical features and therapeutic patterns (1977–2024)

The Journal of Headache and Pain
Introduction Secondary headaches presenting similar clinical findings to migraine are known as migraine-like headaches. Currently, there is no broad consensus regarding their prevalence, characteristics, or underlying causes.
Elliot G. Gama-Reyes, Andrea Nuñez de Caceres-García, María F. Castillo-Vaca, Jacqueline Hernandez-Ramirez, Ariel E. Jimenez-Romo, Jenyfer María Fuentes-Mendoza, Erika Rodríguez-Lizarraga, Carlos A. Díaz-Garza, Javier Andrés Galnares-Olalde   +8 more
doaj   +1 more source

Diagnosis and Management of Migraine Headaches [PDF]

, 2020
: Migraine headaches afflict approximately 6% of men and 18% of women in the United States, and cost billions of dollars each year in lost productivity, absenteeism, and direct medical expenditures.
MD Elizabeth C Lawrence
core  

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda, Yohei Sato, Yoshimasa Imoto, Mayumi Tamari, Shigeharu Fujieda   +4 more
wiley   +1 more source

Sex Differences in the Association of Simultaneous Decline in Blood Pressure and Decline in Cognition during Aging

Annals of Neurology, EarlyView.
Objective Both high and declining blood pressure (BP) are associated with risk of cognitive decline in older adults, and women have higher rates of hypertension and faster cognitive decline in late‐life. In old age, the relationship between changes in BP and changes in cognition is complex, and although sex differences in cognitive function and decline
Nicholas W. Baumgartner, Ana W. Capuano, Lisa L. Barnes, David A. Bennett, Zoe Arvanitakis   +4 more
wiley   +1 more source

Increased risk of all-cause, Alzheimer’s, and vascular dementia in adults with migraine in Korea: a population-based cohort study

The Journal of Headache and Pain, 2022
Background Studies investigating the association between migraine and dementia have reported inconsistent findings. This study aimed to evaluate whether patients with migraine have an increased risk of dementia compared to individuals without migraine ...
Kyungduk Hurh, Sung Hoon Jeong, Seung Hoon Kim, Suk-Yong Jang, Eun-Cheol Park, Sung-In Jang   +5 more
doaj   +1 more source