Results 51 to 60 of about 841,585 (286)

The onset of PI3K‐related vascular malformations occurs during angiogenesis and is prevented by the AKT inhibitor miransertib

EMBO Molecular Medicine, 2022
Low‐flow vascular malformations are congenital overgrowths composed of abnormal blood vessels potentially causing pain, bleeding and obstruction of different organs.
Piotr Kobialka, Helena Sabata, Odena Vilalta, Leonor Gouveia, Ana Angulo‐Urarte, Laia Muixí, Jasmina Zanoncello, Oscar Muñoz‐Aznar, Nagore G Olaciregui, Lucia Fanlo, Anna Esteve‐Codina, Cinzia Lavarino, Biola M Javierre, Veronica Celis, Carlota Rovira, Susana López‐Fernández, Eulàlia Baselga, Jaume Mora, Sandra D Castillo, Mariona Graupera   +19 more
doaj   +1 more source

Lymphatic differentiation and microvascular proliferation in benign vascular lesions of skin and soft tissue: Diagnostic features following the International Society for The Study of Vascular Anomalies Classification—A retrospective studyCapsule Summary

JAAD International, 2023
Background: Discrepancies have been noted between the clinical and histologic diagnosis of vascular malformations. Objective: To evaluate the effectiveness of the International Society for Study of Vascular Anomalies (ISSVA) classification in diagnosing ...
Amalia Mulia Utami, MD, Max M. Lokhorst, MD, PhD, Lorine B. Meijer-Jorna, MD, PhD, Mara A. Kruijt, BSc, Sophie E.R. Horbach, MD, PhD, Onno J. de Boer, PhD, Chantal M.A.M. van der Horst, MD, PhD, Allard C. van der Wal, MD, PhD   +7 more
doaj   +1 more source

Genetic causes of vascular malformations.

, 2007
Vascular malformations are localized defects of vascular development. They usually affect a limited number of vessels in a restricted area of the body. Although most malformations are sporadic, inheritance is observed, enabling genetic analysis. Usually,
Vikkula, Miikka, Brouillard, Pascal
core   +1 more source

Prediction model for complex venous malformation complete remission after sirolimus using clinicopathological and CEUS parameters

Scientific Reports
To develop and validate a machine learning model incorporating clinicopathological features and contrast-enhanced ultrasound (CEUS) parameters for predicting complete remission (CR) following sirolimus therapy in patients with complex venous ...
Bin Sun, Hongzhao Lei, Miaomiao Li, Bingyang Zhang, Changxian Dong   +4 more
doaj   +1 more source

Image guided sclerotherapy for the treatment of venous malformations

CVIR Endovascular, 2018
Background Percutaneous sclerotherapy is the preferred method of treatment for VMs (venous malformations). However, treatment protocols vary, and research on the most effective sclerosant is conflicting.
Johnathon Gorman, Steven J. Zbarsky, Rebecca J. M. Courtemanche, Jugpal S. Arneja, Manraj K. S. Heran, Douglas J. Courtemanche   +5 more
doaj   +1 more source

Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham, Teyl Engstrom, Peter Baade, Natalie Bradford, Sarah Pont, Louise Marquart‐Wilson, Natasha Nassar, Jason D. Pole   +7 more
wiley   +1 more source

Progress in the genetics research of infantile hemangioma and vascular malformations

口腔疾病防治, 2019
The etiology and pathogenesis of hemangiomas and vascular malformations are still unclear and face many challenges in terms of treatment. This article focuses on the etiology and genetic mechanism of common vascular tumors (such as infantile hemangiomas,
ZHENG Jiawei, ZHAO Zeliang
doaj   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Vascular malformations

, 2015
Vascular malformations are rare in fetuses and neonates and can be summarized in two main conditions: the dural sinus malformations and the vein of Galen aneurismal ...
Baldoli C., Triulzi F., Pontesilli S., Scotti R.   +3 more
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source