Results 101 to 110 of about 1,023,794 (259)

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

Occlusion-aware Multifocal Displays

, 2020
The goal of three-dimensional (3D) displays is to recreate reality by satisfying all perceptual cues used by the human visual system. While many perceptual cues can be replicated by showing 2D images to our eyes, the accommodation cue, or the change of ...
Jen-hao Chang (4939651)
core   +1 more source

Effects of exercise training with blood flow restriction on blood pressure in medicated hypertensive patients

Motriz: Revista de Educacao Fisica, 2016
The development of non-pharmacological approaches to hypertension (HA) is critical for both prevention and treatment. This study examined the hemodynamic and biochemical responses of medicated hypertensive women to resistance exercise with blood flow ...
Marcos Antônio Cezar, Clodoaldo Antônio De Sá, Vanessa da Silva Corralo, Sedinei Lopes Copatti, Guilherme Augusto Gonzaga dos Santos, Marzo Edir da Silva Grigoletto   +5 more
doaj   +1 more source

Versatile Co‐Engineering of Immunogenic Cell Death‐Primed Dead Tumor Cell Bodies With Tumor‐Activated MnO2 for cGAS‐STING‐Potentiated Personalized Immunotherapy

Advanced Science, EarlyView.
DTBEI@CS@MnO2, fabricated via modular electrostatic co‐engineering and photothermal/photodynamic immunogenic cell death, specifically responds to the acidic and GSH‐rich tumor microenvironment. This triggers the release of DTBEI that provides tumor antigens, DNA, and DAMPs, as well as the generation of Mn2+, thereby synergistically potentiating cGAS ...
Bolun Xu, Xuan Lu, Yuquan Wang, Haihua Ji, Ying Zhang, Yiqun Wan, Hao Wan   +6 more
wiley   +1 more source

Short-Term Outcomes After Symptomatic Internal Carotid Artery Occlusion

, 2011
Background and Purpose-Previous studies concerning internal carotid artery (ICA) occlusion have focused on long-term prognosis. The purpose of the present study was to evaluate short-term outcomes of patients with symptomatic ICA occlusion.
Kapral, Moira K., Casaubon, Leanne K., Mervyn D.I. Vergouwen, Vergouwen, Mervyn D. I., Burke, Matthew J., Silver, Frank L., Rick H. Swartz, Swartz, Rick H., Jiming Fang, Frank L. Silver, Fang, Jiming, Matthew J. Burke, Leanne K. Casaubon, Moira K. Kapral   +13 more
core   +1 more source

Simultaneous central retinal vein and cilioretinal artery occlusion in a young female patient with progestin-only oral contraceptive use: a case report

Journal of Medical Case Reports
Background Central retinal vein occlusion and cilioretinal artery occlusion are rare but serious ocular conditions that can lead to significant visual impairment.
Sardar Noman Qayyum, Risha Naeem, Faraz Azhar, Gulmeena Aziz Khan, Tehreem Zubair, Samim Noori   +5 more
doaj   +1 more source

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

Advanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu, Ling Li, Sachin S. Surwase, Xin Ming M. Zhou, Hongtao Qian, Joel C. Sunshine, Florin M. Selaru, Jordan J. Green   +7 more
wiley   +1 more source

Amplatzer Vascular Plug for Arteriovenous Hemodialysis Access Occlusion: Initial Experience

, 2009
Purpose The Amplatzer Vascular Plug (AVP; AGA Medical, Golden Valley, MN) is a recently developed self-expanding metallic device indicated for peripheral vascular embolizations.
J.T. Bui, M.G. Knuttinen, C.A. Owens, R.C. Gaba, D.L. West   +4 more
core   +1 more source

Common femoral artery occlusion following suture-mediated vascular closure device: A case report

Radiology Case Reports
Vascular closure devices are widely utilized following endovascular procedures. Device-related femoral artery occlusion is rarely reported with no consensus on the treatment strategy.
Kai Dick David Leung
doaj   +1 more source

Nano Proton Scavengers Modulate Endosomal pH to Inhibit Microglial Activation and Enhance Stroke Recovery

Advanced Science, EarlyView.
Amphiphilic sulfonated chitosan nanoparticles buffer endo/lysosomal acidity in microglia by limiting V‐ATPase membrane recruitment and restoring endosomal homeostasis. Following systemic administration, they accumulate in the ischemic hemisphere partly through association with infiltrating immune cells, suppress TLR3/IRF3 and TLR4/NF‐κB signaling ...
Xuanlin Wang, Yujing Shi, Zehua Gao, Jing Wang, Changsheng Liu   +4 more
wiley   +1 more source