Results 111 to 120 of about 1,023,794 (259)

Feasibility to obtain vessel occlusion using vessel loop

Scientific Reports
This ex-vivo study evaluated the tensile strength required for vascular occlusion using vessel loops on human femoral arterie and porcine aortic arteries.
Albert Pons-Riverola, Agustí Martí, Laia Nogué-Navarro, Joan Leal-Blanquet, Josep Maria Muñoz-Vives   +4 more
doaj   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

Role of Interleukin-18 in vascular injury: a new pharmacological target for the prevention of restenosis [PDF]

, 2006
Background: Studies in humans as well as in animal models suggest that interleukin-18 (IL-18) plays a crucial role in vascular pathologies. IL-18 is a strong predictor of cardiovascular death in angina and is involved in atherotic plaque destabilization.
Grassia, Gianluca
core   +1 more source

A Metal‐Polyphenol Self‐Assembled Coated 3D Sponge With Mild Photothermal Antibacterial, Exudate‐Controlling, and Immunomodulatory Functions for Hemostasis and Chronic Wound Healing

Advanced Science, EarlyView.
A thrombin‐functionalized copper‐polydopamine nanofiber sponge integrates rapid hemostasis, mild photothermal antibacterial therapy, stimulus‐responsive Cu2+ release, chemodynamic oxidative stress, and macrophage immunomodulation. This multifunctional dressing suppresses infection, regulates inflammation, promotes angiogenesis and re‐epithelialization,
Ziwei Zhang, Feng Qin, Xiaomeng Zhang, Xueqin Shuang, Jiahua Zhou, Ming Cheng, Baicheng Lu, Mingyue Song, Yuntian Bai, Dianying Zhang, Ming Li, Yanhua Wang   +11 more
wiley   +1 more source

Nrsn1–Smarcc1 Coupling Regulates Neural Stem Cell Differentiation and Chronic‐phase Recovery After Ischemic Stroke

Advanced Science, EarlyView.
In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang, Chang Liu, Yuneng Zhou, Kaichen Zhao, Muyang Li, Bingcheng Cai, Ying Wang, Zhiyuan Yuan, Zhaoxin Liu, Zilong Yuan, Yao Xiao, Peiyang Zhou, Ke Shui, Wendai Bao, Min Zhang, Jun Qin, Jun Chen, Xin Yang, Zhiqiang Dong   +18 more
wiley   +1 more source

Self‐Propelled HPB@Lip@AB Nanomotors Ameliorate Dry Eye Disease

Advanced Science, EarlyView.
A self‐propelled HPB@Lip@AB nanomotor system is developed for dry eye disease (DED) therapy, facilitating rapid penetration across ocular surface barriers while integrating hydrogen therapy with multi‐enzyme‐like antioxidant activity. The nanoplatform restores mitochondrial function, suppresses oxidative stress, inflammation, and apoptosis, and ...
Jing Li, Xi Wan, Xinru Su, Zechuan Li, Yue Wang, Ying Wang, Ruofei Li, Huangzhao Wei, Jianbin Zhang, Shuai Wang   +9 more
wiley   +1 more source

Endoluminal occlusion devices: technology update

, 2014
Tobias Zander,1 Samantha Medina,1 Guillermo Montes,1 Lourdes Nuñez-Atahualpa,1 Michel Valdes,1 Manuel Maynar1,2 1Endoluminal/Vascular Department, Hospiten Hospital Group, Santa Cruz de Tenerife, 2University of Las Palmas de Gran Canarias, Las ...
Zander T, Valdes M, Montes G, Nuñez-Atahualpa L, Maynar M, Medina S   +5 more
core  

Unilateral Adrenalectomy, and the Stable Pentadecapeptide BPC 157 as Therapy in Rats—A Cytoprotection Approach

Pharmaceuticals
Background. This rat study reveals a new point: the considerable impact of unilateral adrenalectomy, severe vascular and multiorgan failure, occlusion/occlusion-like syndrome, and the stable gastric pentadecapeptide BPC 157 therapy.
Ivan Maria Smoday, Vlasta Vukovic, Katarina Oroz, Hrvoje Vranes, Luka Kalogjera, Ozren Gamulin, Josipa Vlainic, Marija Milavic, Suncana Sikiric, Nora Nikolac Gabaj, Domagoj Marijancevic, Antun Koprivanac, Laura Tomic, Sanja Strbe, Ivan Barisic, Lidija Beketic Oreskovic, Mario Kordic, Ante Tvrdeic, Sven Seiwerth, Predrag Sikiric, Alenka Boban Blagaic, Anita Skrtic   +21 more
doaj   +1 more source

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis

Advanced Science, EarlyView.
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang, Jian‐Tong Shen, Hua‐Hua Zhang, Si‐Qi Gao, Ji‐Ao Wang, Yue‐Ling Wang, Mei‐Ling Li, Zi‐Meng Liu, Yi‐Nan Zhang, Yan Li, Xu‐Yu Zhang   +10 more
wiley   +1 more source

Preoperative FIB‐4 Index as a Potential Factor Associated With Severe Postoperative Complications and Endogenous Organ Failure After Hepatectomy for Hepatocellular Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
This study demonstrates that a preoperative FIB‐4 index ≥ 5.0 independently predicts severe complications and endogenous organ failure (EOF) following hepatectomy for hepatocellular carcinoma. By capturing structural liver fragility and systemic vulnerability, the FIB‐4 index enhances surgical risk stratification beyond traditional functional markers ...
Masanori Nakamura, Yukiyasu Okamura, Osamu Aramaki, Nao Yoshida, Yusuke Mitsuka, Hayato Abe, Shunsuke Yamagishi, Yasuhiro Okumura, Kyongsun Pak, Shinobu Masuda   +9 more
wiley   +1 more source