Results 91 to 100 of about 2,306,257 (312)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Large herbivore grazing affects the vegetation structure and greenhouse gas balance in a high arctic mire

Environmental Research Letters, 2015
Herbivory is an important part of most ecosystems and affects the ecosystems’ carbon balance both directly and indirectly. Little is known about herbivory and its impact on the carbon balance in high arctic mire ecosystems. We hypothesized that trampling
Julie Maria Falk, Niels Martin Schmidt, Torben R Christensen, Lena Ström   +3 more
doaj   +1 more source

Impact of COVID-19 on vascular patients worldwide: analysis of the COVIDSurg data.

, 2021
BACKGROUND: The COVIDSurg collaborative was an international multicenter prospective analysis of perioperative data from 235 hospitals in 24 countries. It found that perioperative COVID-19 infection was associated with a mortality rate of 24%.
Elmore U, The COVIDSurg Collaborative and Vascular and Endovascular, Research Network, Matthew MACHIN, Bosanquet, David, Machin, Matthew, The COVIDSurg Collaborative, Hitchman, Louise, Louise HITCHMAN, Vascular and Endovascular Research Network   +8 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Vascular risk and depression in outpatients at Groote Schuur Hospital memory clinic [PDF]

, 2009
Includes bibliographical references (leaves 59-67).Background and Objective: Depression in the elderly has been linked with stroke, and with white matter lesions, particularly in frontal-subcortical regions responsible for mood regulation.
Kinnear, H
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Vascular Plants and Biocrusts Modulate How Abiotic Factors Affect Wetting and Drying Events in Drylands [PDF]

, 2014
Understanding how organisms control soil water dynamics is a major research goal in dryland ecology. Although previous studies have mostly focused on the role of vascular plants on the hydrological cycle of drylands, recent studies highlight the ...
Maestre, Fernando T., Berdugo, Miguel, Soliveres, Santiago   +2 more
core   +2 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Vascular Plants

, 2016
This report contains the vascular plant Red List for Ireland. The threat status of native and archaeophyte (pre-1500 introductions) vascular plant species, subspecies and certain hybrids recorded from the wild on the island of Ireland is assessed, following current International Union for the Conservation of Nature (IUCN) categories and criteria, and ...
Wyse Jackson, Michael, FitzPatrick, Úna, Cole, Edwina, Jebb, Matthew, McFerran, Damian, Sheehy Skeffington, Micheline, Wright, Mark, Ireland. National Parks and Wildlife Service, National Biodiversity Data Centre (Ireland), National Botanic Gardens (Ireland), National Museums Northern Ireland. Centre for Environmental Data and Recording, National University of Ireland, Galway. School of Natural Sciences. Plant Ecology Research Unit, Northern Ireland. Environment Agency. Natural Environment Division   +12 more
openaire   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source