Results 51 to 60 of about 107,330 (317)

Plants in the clouds: vascular epiphytes of Pedra Azul, a mountain top in Espírito Santo, Southeastern Brazil [PDF]

, 2022
Gabriel Mendes Marcusso, Luiz Menini Neto, Júlio Antônio Lombardi   +2 more
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Side by side? Vascular plant, invertebrate, and microorganism distribution patterns along an alpine to nival elevation gradient

Arctic, Antarctic, and Alpine Research, 2018
High mountain areas above the alpine zone are, despite the low-temperature conditions, inhabited by evolutionary and functionally differing organism groups.
Manuela Winkler, Paul Illmer, Pascal Querner, Barbara M. Fischer, Katrin Hofmann, Andrea Lamprecht, Nadine Praeg, Johannes Schied, Klaus Steinbauer, Harald Pauli   +9 more
doaj   +1 more source

Macrophytes of the lakes Trnovačko jezero, Veliko Stabanjsko jezero, and Malo Stabanjsko jezero on Mt. Volujak (Montenegro) [PDF]

Archives of Biological Sciences, 2005
The present paper gives results of floristic investigations of macrophytes in lakes on Mt. Volujak, the spatial distribution of the recorded species, and basic ecological characteristics of the milieu of life in the investigated biotopes.
Blaženčić Jelena M., Blaženčić Živojin   +1 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Vascular Plants of the Town of Belomorsk, Republic of Karelia

Transactions of the Karelian Research Centre of the Russian Academy of Sciences, 2016
Information on 505 taxa of wild-growing vascular plants from the Town of Belomorsk is reported. Generalized habitat types and frequency of occurrence are stated for each taxon. Herbarium labels stating the sample storage location are cited for the rarest
Alexey Kravchenko, Vera Timofeeva, Oksana Rudkovskaya, Margarita Fadeeva   +3 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

A preliminary vascular flora of the Parque Ecológico Ermida Dom Bosco, Distrito Federal, Brazil

Heringeriana, 2020
The area known as Parque Ermida Dom Bosco on the shores of the Paranoá Lake, 7.8 km from the centre of Brasí­lia (Rodoviária do Plano Piloto), Distrito Federal, Brazil, is a preservation area of Monumento Natural category (since 2019), and one of the ...
Karina Shizue Gadelha Kubota, Leonardo Ferreira-Sousa, Maria das Graças Machado de Souza, Claudenir Simões Caires, Carolyn Elinore Barnes Proença   +4 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source