Results 61 to 70 of about 306,598 (313)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
The differential effects of CBD and CBDA on viability and mRNA expression in colorectal cancer cells
Journal of Cannabis ResearchBackground Cannabinoids have attracted significant attention for their potential therapeutic application in cancer research. However, recent studies have reported antitumor activity of cannabidiolic acid (CBDA)—the acidic precursor of CBD—in breast ...
Christine Heinzle +8 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Structural dynamics and divergence of the polygalacturonase gene family in land plants [PDF]
, 2008 A distinct feature of eukaryotic genomes is the presence of gene families. The polygalacturonase (PG) (EC3.2.1.15) gene family is one of the largest gene families in plants. PG is a pectin-digesting enzyme with a glycoside hydrolase 28 domain.
Hae-Young Oh +6 more
core +1 more source
Adaptation of the "Herbarium" Computer DataBase to Archiving and Analysis of Floristic Data [PDF]
, 2010 The aim of the study was to present "Herbarium" computer database. The basic goal of construction of the database was gathering and analysing of archival and contemporary floristic data referring to the area of Central Poland.
Jakubowska-Gabara, Janina +2 more
core +2 more sources
On the trails of Josias Braun-Blanquet II : first results from the 12th EDGG Field Workshop studying the dry grasslands of the inneralpine dry valleys of Switzerland [PDF]
, 2020 The 12th EDGG Field Workshop took place from 11 to 19 May 2019, organised by the Vegetation Ecology Group of the Institute of Natural Resource Sciences (IUNR) of the Zurich University of Applied Sciences (ZHAW). Like in the 11th Field Workshop in Austria,
Babbi, Manuel +14 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Contributions to the Flora of Cimarron County and the Black Mesa Area
Oklahoma Native Plant Record, 2015 This paper reports the results of recent collection activities in Cimarron County, including the Black Mesa area, in the state of Oklahoma. A total of 331 taxa in 60 families were collected.
Amy K. Buthod, Bruce W. Hoagland
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source