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Chemokines in vascular remodeling
Thrombosis and Haemostasis, 2007SummaryThe arterial vessel wall response to a variety of injuries consists in structural changes, which can result in luminal narrowing and aggravation of the underlying disease.This arterial remodeling is characterized by neointima formation and medial thickening, inflammatory cell recruitment and endothelial dysfunction.
Andreas, Schober, Alma, Zernecke
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Vascular remodelling in asthma
Current Opinion in Allergy & Clinical Immunology, 2008We review the recent literature, focusing on 2006 and 2007, to produce an update on the patho-biology of angiogenesis and vascular endothelial growth factor in the asthmatic airway.In terms of conceptual development in asthma research, airway inflammation and remodelling have been regarded as separate processes or perhaps as sequential, with early ...
Walters, Eugene H +3 more
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Vascular remodeling and mineralocorticoids
Journal of Endocrinological Investigation, 1995Circulating mineralocorticoid hormones are so named because of their important homeostatic properties that regulate salt and water balance via their action on epithelial cells. A broader range of functions in nonclassic target cellular sites has been proposed for these steroids and includes their contribution to wound healing following injury.
K T, Weber +4 more
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PECAM-1 Is Necessary for Flow-Induced Vascular Remodeling [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2009 Objective—Vascular remodeling is a physiological process that occurs in response to long-term changes in hemodynamic conditions, but may also contribute to the pathophysiology of intima-media thickening (IMT) and vascular disease.
Ellie Tzima, Zhongming Chen
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Vascular Remodeling in Varicose Veins
Angiology, 1998The present study describes the histopathologic aspects of varicose (n=29; mean age, 52 ± 12 years) and normal saphenous veins (n=17; mean age, 51 ± 12 years) of patients from a similar age group. We focused on the changes that occur in the circular layer of the venous wall.
Kockx, M.M. +5 more
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Targeting Vascular Remodeling to Treat Pulmonary Arterial Hypertension [PDF]
Trends in Molecular Medicine, 2017 Pulmonary arterial hypertension (PAH) describes a group of conditions with a common hemodynamic phenotype of increased pulmonary artery pressure, driven by progressive remodeling of small pulmonary arteries, leading to right heart failure and death ...
Allan Lawrie +2 more
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Seminars in Pediatric Surgery, 2007
The maladaptive response of the pulmonary vasculature that occurs in patients with congenital diaphragmatic hernia significantly impacts outcome. Muscularized distal pulmonary arterioles inhibit the ability of the neonate to adjust to extrauterine circulation, resulting in severe pulmonary hypertension.
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The maladaptive response of the pulmonary vasculature that occurs in patients with congenital diaphragmatic hernia significantly impacts outcome. Muscularized distal pulmonary arterioles inhibit the ability of the neonate to adjust to extrauterine circulation, resulting in severe pulmonary hypertension.
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Vascular remodelling in hypertension
European Heart Journal, 1993Essential hypertension is associated with alterations in the structure of the resistance vasculature, such that the ratio of the media thickness to the lumen diameter (media:lumen ratio) is increased. These abnormalities have previously been explained in terms of vascular growth (an encroachment of the wall into the lumen), but the abnormalities could ...
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2019
Vascular remodelling plays an important role in the adaptation of the athlete to increased exercise duration and intensity. Endurance exercise improves endothelium-dependent flow-mediated vasodilation and leads to increases in conduit artery lumen diameter after regular exercise, typically in the trained limb. These changes result in a reduced vascular
Gielen, S +2 more
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Vascular remodelling plays an important role in the adaptation of the athlete to increased exercise duration and intensity. Endurance exercise improves endothelium-dependent flow-mediated vasodilation and leads to increases in conduit artery lumen diameter after regular exercise, typically in the trained limb. These changes result in a reduced vascular
Gielen, S +2 more
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Redox regulation of vascular remodeling
Cellular and Molecular Life Sciences, 2015Vascular remodeling is a dynamic process of structural and functional changes in response to biochemical and biomechanical signals in a complex in vivo milieu. While inherently adaptive, dysregulation leads to maladaptive remodeling. Reactive oxygen species participate in homeostatic cell signaling in tightly regulated- and compartmentalized cellular ...
Keyvan, Karimi Galougahi +2 more
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