Results 161 to 170 of about 4,433,818 (382)
Ovarian cancer's high recurrence and therapy resistance demand new strategies. A high‐throughput drug screening pipeline using 3D spheroids, which showed poor concordance with 2D models, identified rapamycin as a promising candidate. In combination with cisplatin, rapamycin demonstrated significant in vitro and in vivo efficacy, highlighting the ...
Nazanin Karimnia+9 more
wiley +1 more source
The reflex effects of alterations in lung volume on systemic vascular resistance in the dog [PDF]
M. de Burgh Daly+2 more
openalex +1 more source
Segmented PCL‐bisurea (BU) polymers and BU‐peptide conjugate additives assemble into fibrous superstructures at the nanoscale through a mix‐and‐matching strategy. Different bioactivities are incorporated through variation of peptide sequences. The resulting materials are screened for their effect on stem cell adhesion and pluripotency.
Johnick F. van Sprang+6 more
wiley +1 more source
Effects of Propranolol and Its Stereoisomers upon Coronary Vascular Resistance [PDF]
Leighton S. Whitsitt+1 more
openalex +1 more source
In this study, a cuff‐free, less‐invasive surgical approach for vagus nerve stimulation (VNS) by combining ultrathin Y‐shaped kirigami electrodes is developed with a chemically cross‐linked hydrogel adhesive (hydrogel‐kirigami). Unlike conventional cuff implantation, which may damage nerves and nearby critical vessels, this new technique minimizes ...
Jae Young Park+9 more
wiley +1 more source
Effects of Acetylstrophanthidin on Coronary Vascular Resistance and Myocardial Oxygen Consumption [PDF]
John A. Waldhausen+3 more
openalex +1 more source
Engineering the Future of Restorative Clinical Peripheral Nerve Surgery
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell+5 more
wiley +1 more source
Restoring Connectivity in Vascular Segmentation using a Learned Post-Processing Model [PDF]
Accurate segmentation of vascular networks is essential for computer-aided tools designed to address cardiovascular diseases. Despite more than thirty years of research, it remains a challenge to obtain vascular segmentation results that preserve the connectivity of the underlying vascular network.
arxiv
Longitudinal distribution of vascular resistance in the pulmonary arteries, capillaries, and veins [PDF]
Jerome S. Brody+2 more
openalex +1 more source
Nanobubbles functionalized with indocyanine green and ischemic myocardium‐targeting peptide effectively target cardiomyocytes and enable the multimodal (fluorescence, ultrasonic, and photoacoustic) imaging of ischemic myocardium in mice with coronary microvascular dysfunction (CMD).
Bo Yu+8 more
wiley +1 more source