Results 181 to 190 of about 4,433,818 (382)

Hybrid roles of adaptation and optimization in formation of vascular network [PDF]

arXiv
It was hypothesized that the structures of biological transport networks are the result of either energy consumption or adaptation dynamics. Although approaches based on these hypotheses can produce optimal network and form loop structures, we found that neither possesses complete ability to generate complex networks that resemble vascular network in ...
arxiv  

Mitral valve replacement: Long-term results, with particular reference to changes in pulmonary vascular resistance [PDF]

, 1968
John Hamer, T. J. C. BOULTON, Jennifer C. Fleming, G. W. Hayward, Ian Hill, I. Monro, G. Simon, C. S. Tubbs   +7 more
openalex   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Inorganic Nanomaterials Meet the Immune System: An Intricate Balance

Advanced Healthcare Materials, EarlyView.
Metal nanomaterials influence the immune responses, such as cytokine production and T‐cell activity. Unintended immune modulation can have significant consequences while its fine‐tuning may transform the oncology care. Within this review, a critical analysis is offered regarding the nano/immune‐interaction and suggests the future research directions to
Gloria Pizzoli, Marco Gargaro, Giuliana Drava, Valerio Voliani   +3 more
wiley   +1 more source

Omics and Extreme Phenotyping Reveal Longitudinal Association Between Left Atrial Size and Pulmonary Vascular Resistance in Group 2 Pulmonary Hypertension. [PDF]

J Am Heart Assoc, 2023
Kelly NJ, Newhouse D, Chapagain H, Patel A, Tang Y, Howard A, Kirillova A, Kim HJ, Rahman H, El Khoury W, Nouraie SM, Hickey G, Sade LE, Jain S, Chan SY.   +14 more
europepmc   +1 more source

Increased Vascular Resistance by Prostaglandins B1 and B2 in the Isolated Rat Pancreas [PDF]

, 1972
R. N. Saunders, Chuanpit Moser
openalex   +1 more source

Short‐Chain Fatty Acids Modulate Anti‐ROR1 CAR T‐Cell Function and Exhaustion in an Intestinal Adenocarcinoma‐on‐Chip Model

Advanced Healthcare Materials, EarlyView.
Short‐chain fatty acids modulate anti‐ROR1 chimeric antigen receptor (CAR) T‐cell function in an intestinal adenocarcinoma‐on‐chip model. Butyrate and propionate reduce cytotoxicity, cytokine release, and infiltration by inducing a regulatory T‐cell phenotype and T‐cell exhaustion via histone deacetylase inhibition.
Valentin D. Wegner, Adrian Feile, Miriam Alb, Michael Hudecek, Philip Hewitt, Alexander S. Mosig   +5 more
wiley   +1 more source

Skin Vascular Resistance Decreases during 5-HT-Induced Hypotension in the Rat. [PDF]

Biomedicines, 2023
Butler B, Garver H, Watts SW, Fink GD.
europepmc   +1 more source

Relation of renin status to neurogenic vascular resistance in borderline hypertension [PDF]

, 1975
Murray Esler, Stevo Julius, Otelio S. Randall, Charles N. Ellis, Tomoyoshi Kashima   +4 more
openalex   +1 more source

Functionalized Cerium Oxide Nanoparticles Enhance Penetration into Melanoma Spheroids In Vivo through Angiogenesis

Advanced Healthcare Materials, EarlyView.
Melanoma cell spheroid engraftment is optimized in the chicken chorioallantoic membrane overcoming the complexity of other in vivo models. Using this model, greater penetration of cerium oxide nanoparticles (nanoceria) functionalized with heparin in spheroids is observed via enhancement of vascularization than nanoceria alone.
Lu Fu, Joel M. Yong, Robyn Yeh, Florence Bartlett, John M. Whitelock, Megan S. Lord   +5 more
wiley   +1 more source