Results 11 to 20 of about 4,471,992 (283)

Vascular stiffness in insulin resistance and obesity [PDF]

open access: yesFrontiers in Physiology, 2015
Obesity, insulin resistance, and type 2 diabetes are associated with a substantially increased prevalence of vascular fibrosis and stiffness, with attendant increased risk of cardiovascular and chronic kidney disease. Although the underlying mechanisms and mediators of vascular stiffness are not well understood, accumulating evidence supports the role ...
Annayya R. Aroor   +5 more
openaire   +4 more sources

Predicting the vascular adhesion of deformable drug carriers in narrow capillaries traversed by blood cell [PDF]

open access: yesJournal of Fluid and Structures 82 (2018) 638-650, 2022
In vascular targeted therapies, blood-borne carriers should realize sustained drug release from the luminal side towards the diseased tissue. In this context, such carriers are required to firmly adhere to the vessel walls for a sufficient period of time while resisting force perturbations induced by the blood flow and circulating cells. Here, a hybrid
arxiv   +1 more source

Obesity, Adipose Tissue and Vascular Dysfunction.

open access: yesCirculation Research, 2021
Cardiovascular diseases are the leading cause of death worldwide. Overweight and obesity are strongly associated with comorbidities such as hypertension and insulin resistance, which collectively contribute to the development of cardiovascular diseases ...
M. Koenen, M. Hill, P. Cohen, J. Sowers
semanticscholar   +1 more source

Evaluation of resistive index of orbital vessels using color doppler imaging in patients with type 2 diabetes mellitus

open access: yesJournal of Medical Ultrasound, 2021
Background: Resistive index (RI), derived from color Doppler imaging (CDI), is a marker of vascular resistance used widely in varied clinical settings.
Vikrant Kanagaraju   +3 more
doaj   +1 more source

Dynamic Arterial Elastance Is Associated With the Vascular Waterfall in Patients Treated With Norepinephrine: An Observational Study

open access: yesFrontiers in Physiology, 2021
Introduction: It has been suggested that dynamic arterial elastance (Eadyn) can predict decreases in arterial pressure in response to changing norepinephrine levels.
Stéphane Bar   +7 more
doaj   +1 more source

The effect of different dosages of progesterone suppositories on uterine-fetal vascular resistance in women at risk of premature delivery and its comparison with the control group [PDF]

open access: yesMajallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2023
Introduction: Despite the widespread use of progesterone in pregnancy, there is limited information on its effect on uterine-placental blood circulation and especially on the fetal blood circulation system in the second half of pregnancy.
Mozhgan Rahmanian   +3 more
doaj   +1 more source

Larger First-Trimester Placental Volumetric Parameters Are Associated With Lower Pressure and More Flow-Mediated Vasodilation of the Fetoplacental Vasculature After Delivery

open access: yesFrontiers in Physiology, 2020
ObjectiveTo explore the correlation between in vivo placental volumetric parameters in the first trimester of pregnancy and ex vivo parameters of fetoplacental vascular function after delivery.MethodsIn ten singleton physiological pregnancies, placental ...
Emilie Hitzerd   +9 more
doaj   +1 more source

Calcium signals that determine vascular resistance

open access: yesWiley Interdisciplinary Reviews: Systems Biology and Medicine, 2019
Small arteries in the body control vascular resistance, and therefore, blood pressure and blood flow. Endothelial and smooth muscle cells in the arterial walls respond to various stimuli by altering the vascular resistance on a moment to moment basis ...
Matteo Ottolini   +2 more
semanticscholar   +1 more source

Effects of empagliflozin on blood pressure and markers of arterial stiffness and vascular resistance in patients with type 2 diabetes

open access: yesDiabetes, obesity and metabolism, 2015
To determine the effects of empagliflozin on blood pressure (BP) and markers of arterial stiffness and vascular resistance in patients with type 2 diabetes mellitus (T2DM).
R. Chilton   +6 more
semanticscholar   +1 more source

Mechanisms of chemotherapy resistance in ovarian cancer

open access: yesCancer Drug Resistance, 2022
Ovarian cancer is one of the most lethal gynecologic cancers. The standard therapy for ovarian cancer has been the same for the past two decades, a combination treatment of platinum with paclitaxel. Recently, the FDA approved three new therapeutic drugs,
M. Ortiz   +3 more
semanticscholar   +1 more source

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