Vascular Targeted Agents for the Treatment of Angiosarcoma [PDF]
Background: Angiogenesis is the process of new blood vessel formation, and is regulated by angiogenic growth factors including vascular endothelial growth factor (VEGF). Angiosarcomas are rare, aggressive vascular tumours.
P J Woll (16226153) +5 more
core +6 more sources
The anti-atherogenic effects of thiazolidinediones [PDF]
The thiazolidinediones (TZDs) rosiglitazone (ROS) and pioglitazone (PIO) are insulin-sensitising agents widely used to treat patients with type 2 diabetes mellitus (T2DM). Thiazolidinediones significantly improve glycaemic control in diabetics by reduced
Stojanovska, Lily +2 more
core +6 more sources
Highly effective non-viral gene transfer into vascular smooth muscle cells of cultured resistance arteries demonstrated by genetic inhibition of sphingosine-1-phosphate-induced vasoconstriction [PDF]
The linkage of vascular genes to specific functions will lead to a better understanding of cardiovascular pathophysiology. We developed an experimental model that enables the introduction of one or multiple gene(s) into vascular smooth muscle cells ...
Pohl, U., Bolz, S. S.
core +2 more sources
Effects of Tissue Component Volumes on Vascular Resistance in Free Flaps [PDF]
Background:A successful free flap transfer is achieved, in part, by having a thorough understanding of vascular anatomy and blood flow dynamics. We previously reported that vascular resistance differs by type of free flap. To test the hypothesis that the
Ono, Masashi +8 more
core +1 more source
Hypothesis: ‘Vasocrine’ signalling from perivascular fat - a mechanism linking insulin resistance and vascular disease [PDF]
Adipose tissue expresses cytokines which inhibit insulin signalling pathways in liver and muscle. Obesity also results in impairment of endothelium-dependent vasodilatation to insulin. We propose a vasoregulatory role for local deposits of fat around the
Stehouwer, C.D.A. +7 more
core +1 more source
Brain Tumor Vascular Network Segmentation from Micro-Tomography [PDF]
Micro-tomography produces high resolution images of bio- logical structures such as vascular networks. In this paper, we present a new approach for segmenting vascular network into pathological and normal regions from considering their micro-vessel 3D ...
Raphael Serduc +14 more
core +1 more source
Comparison of Carotid Artery Intima-media Thickness and Resistive Index by Ultrasound and Colour Doppler in Pre-hypertensives and Stage One Hypertensives [PDF]
Introduction: Pre-hypertension and stage one hypertension remains major public health problem in both developed and developing countries. It primarily affects elastic arteries, hence common carotid artery Intima-Media Thickness (IMT) and Resistive ...
Subha Venkatachalam +5 more
doaj +1 more source
Introducción. Existen pocos datos con respecto a los efectos de la carbamacepina y sus derivados en el aparato cardiovascular; además, el mecanismo molecular y su sitio de acción celular no son claros. Objetivo.
Lauro Figueroa-Valverde +4 more
doaj +1 more source
Vascular resistance in essential hypertension: relationship between overall peripheral and regional vascular resistance.
V. F. Lukyanov +2 more
doaj +1 more source
Changes in Vascularization of Human Breast Cancer Xenografts Responding to Antiestrogen Therapy
To elucidate the previously suggested vascular effect(s) of antiestrogen therapy, we studied the effect of estrogen withdrawal and tamoxifen on 1) vascular resistance, 2) glucose and oxygen consumption, 3) vascular density in a perfused breast cancer ...
Claus A. Kristensen +6 more
doaj +1 more source

