Results 51 to 60 of about 4,471,992 (283)

Perioperative challenges and outcome after surgical correction of post-myocardial infarction ventricular septal rupture: A retrospective single center study

Annals of Cardiac Anaesthesia
Background: Ventricular septal rupture (VSR) is a rare but grave complication of acute myocardial infarction (AMI). It is a mechanical complication of myocardial infarction where patients may present either in a compensated state or in cardiogenic shock.
Kedar Bangal
doaj   +1 more source

Development of human brain organoids with functional vascular-like system

Nature Methods, 2019
Human cortical organoids (hCOs), derived from human embryonic stem cells (hESCs), provide a platform to study human brain development and diseases in complex three-dimensional tissue.
Bilal Cakir, Yangfei Xiang, Yoshiaki Tanaka, M. Kural, Maxime J Parent, Young‐Jin Kang, Kayley Chapeton, Benjamin Patterson, Yifan Yuan, Changshun He, M. Raredon, Jake Dengelegi, Kun-Yong Kim, Pingnan Sun, Mei Zhong, Sang-hun Lee, P. Patra, F. Hyder, L. Niklason, Sang-hun Lee, Y. Yoon, In-Hyun Park   +21 more
semanticscholar   +1 more source

Regulation of Pulmonary Vascular Smooth Muscle Contractility in Pulmonary Arterial Hypertension: Implications for Therapy

Frontiers in Physiology, 2017
There are two primary components that produce pulmonary arterial hypertension (PAH); aberrant structural changes (smooth muscle cell proliferation, smooth muscle cell hypertrophy, and the deposition of matrix proteins within the media of pulmonary ...
Melissa A. Lyle, Jonathan P. Davis, Frank V. Brozovich   +2 more
doaj   +1 more source

Severe Hepatic Insulin Resistance Induces Vascular Dysfunction: Improvement by Liver-Specific Insulin Receptor Isoform A Gene Therapy in a Murine Diabetic Model

Cells, 2021
Background: Cardiovascular dysfunction is linked to insulin-resistant states. In this paper, we analyzed whether the severe hepatic insulin resistance of an inducible liver-specific insulin receptor knockout (iLIRKO) might generate vascular insulin ...
Almudena Gómez-Hernández, Natalia de las Heras, Andrea R. López-Pastor, Gema García-Gómez, Jorge Infante-Menéndez, Paula González-López, Tamara González-Illanes, Vicente Lahera, Manuel Benito, Óscar Escribano   +9 more
doaj   +1 more source

Mechanisms of Vascular Aging.

Circulation Research, 2018
Aging of the vasculature plays a central role in morbidity and mortality of older people. To develop novel treatments for amelioration of unsuccessful vascular aging and prevention of age-related vascular pathologies, it is essential to understand the ...
Z. Ungvari, S. Tarantini, A. Donato, V. Galvan, A. Csiszar   +4 more
semanticscholar   +1 more source

3D Printed Architectured Silicones with Autonomic Self-healing and Creep-resistant Behavior [PDF]

arXiv, 2023
Self-healing silicones that are able to restore the functionalities and extend the lifetime of soft devices hold great potential in many applications. However, currently available silicones need to be triggered to self-heal or suffer from creep-induced irreversible deformation during use.
arxiv  

Feedback induced phase transitions in active porous media [PDF]

Phys. Rev. Lett. 114, 134501 (2015), 2014
Flow through passive porous media is typically described in terms of a linear theory relating current fluxes and driving forces, in the presence of a prescribed heterogeneous permeability. However, many porous systems such as glacial drainage networks, erosional river bed networks, vascular networks, social insect swarms and animal architectures such ...
arxiv   +1 more source

Effect of Angiotensin II on Blood Flow in Acute and Chronically Inflamed Knee Joints of Rabbits: The Role of Nitric Oxide [PDF]

Iranian Journal of Medical Sciences, 2009
Background: Angiotensin converting enzyme (ACE) upregulationin stromal cells of joints affected by rheumatoid arthritismay lead to higher tissue angiotensin II that is a vasoconstrictorand mitogen factor.
Hamid Najafipour, Farnaz Nikbakht, Najmeh Sadeghi, Gholam Abbas Dehghani   +3 more
doaj  

Echocardiography based estimation of pulmonary vascular resistance in patients with pulmonary hypertension: a simultaneous Doppler echocardiography and cardiac catheterization study.

European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology, 2011
AIMS Pulmonary vascular resistance (PVR) is an important measurement for the diagnosis of patients with pulmonary hypertension (PH) but needs accurate determination of mean pulmonary artery pressure (PAMP).
P. Lindqvist, S. Söderberg, Manuel C Gonzalez, E. Tossavainen, M. Henein   +4 more
semanticscholar   +1 more source

Scalable Simulation of Realistic Volume Fraction Red Blood Cell Flows through Vascular Networks [PDF]

, 2019
High-resolution blood flow simulations have potential for developing better understanding biophysical phenomena at the microscale, such as vasodilation, vasoconstriction and overall vascular resistance. To this end, we present a scalable platform for the simulation of red blood cell (RBC) flows through complex capillaries by modeling the physical ...
arxiv   +1 more source