Results 51 to 60 of about 3,425,425 (249)

Single-Cell RNA Sequencing Revealed CD14+ Monocytes Increased in Patients With Takayasu’s Arteritis Requiring Surgical Management

Frontiers in Cell and Developmental Biology, 2021
Objectives: Takayasu Arteritis (TA) is a highly specific vascular inflammation and poses threat to patients’ health. Although some patients have accepted medical treatment, their culprit lesions require surgical management (TARSM).
Gao Qing, Gao Qing, Gao Qing, Gao Qing, Wu Zhiyuan, Yu Jinge, Miao Yuqing, Miao Yuqing, Chen Zuoguan, Diao Yongpeng, Yin Jinfeng, Yin Jinfeng, Jia Junnan, Guo Yijia, Guo Yijia, Li Weimin, Li Weimin, Li Yongjun, Li Yongjun   +18 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Physiology, Peripheral Vascular Resistance

, 2023
Peripheral vascular resistance (systemic vascular resistance, SVR) is the resistance in the circulatory system that is used to create blood pressure, the flow of blood and is also a component of cardiac function.
Delong, Claire, Sharma, Sandeep
core   +1 more source

Characteristics of retrobulbar blood flow according to ultrasonic Doppler data in normal conditions

Наука и инновации в медицине
Aim: to establish reference characteristics of blood flow in the retrobulbar vessels and angular artery of the eye based on ultrasound Doppler imaging data in healthy people. Material and methods.
I. P. Vakulenko, A. S. Zolotukhin, V. M. Fominov   +2 more
doaj   +1 more source

Socioeconomic position in childhood and adult cardiovascular risk factors, vascular structure, and function: cardiovascular risk in Young Finns study [PDF]

, 2005
Objective: To examine the association of childhood socioeconomic position (SEP) with adult cardiovascular risk factors, vascular structure, and vascular function in a contemporary population of young adults. Design: Population based prospective cohort
Keltikangas-Järvinen, L., Kivimäki, M, Ferrie, J E, Keltikangas-Järvinen, L, Raitakari, O.T., Raitakari, O T, Elovainio, M., Viikari, J.S.A., Vahtera, J, Elovainio, M, Juonala, M., Viikari, J S A, Vahtera, J., Leino, M, Pulkki-Råback, L., Smith, Davey G, Davey Smith, G., Ferrie, J.E., Juonala, M, Leino, M., Pulkki-Råback, L, Kivimäki, M.   +21 more
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Use of Prostaglandin E1 in Neonates with Severe Persistent Pulmonary Hypertension (PPHN): A Narrative Review [PDF]

Journal of Clinical and Diagnostic Research
Persistent Pulmonary Hypertension of the Newborn (PPHN) is a significant health issue characterised by the inadequate circulatory transitions at birth, subsequent to considerable hypoxaemia and increased Pulmonary Vascular Resistance (PVR).
Ravi Kiran Kumar Reddy, Sagar Karotkar, Mahaveer Lakhra, Aditi Rawat, Nayakawadi Akhil   +4 more
doaj   +1 more source

Investigation of effect of hyperinsulinaemia on adipose tissue microvasculature. [PDF]

, 2015
Background: Obesity in Qatar is amongst the highest globally and constitutes a serious health risk. Obese individuals are at greater risk of vascular disease compared to the lean, especially in the insulin resistant state.
Bakhamis, AAA
core  

Interaction between maternal and offspring diet to impair vascular function and oxidative balance in high fat fed male mice

, 2012
Aims: to determine the impact of maternal and post-weaning consumption of a high fat diet on endothelium-dependent vasorelaxation and redox regulation in adult male mouse offspring.Methods: female C57BL6J mice were fed an obesogenic high fat diet (HF, 45%
Geraldine F Clough, Clough, G.F., Torrens Christopher, Mann, Giovanni E.; id_orcid, Hanson Mark A., Mann Giovanni E., Kimberley D Bruce, Cagampang Felino R. A., Christopher Torrens (114420), Mann, G.E., Ethirajan Priya, Richard C M Siow, Geraldine F. Clough (114433), Byrne Christopher D., Christopher D. Byrne (114429), Siow, Richard C. M.; id_orcid, Felino R. A. Cagampang (114423), Ethirajan, Priya, Cagampang, Felino R. A., Mark A. Hanson (114427), Bruce, K.D., Byrne, Christopher D., Richard C. M. Siow (114425), Giovanni E. Mann (114431), Priya Ethirajan, Mark A Hanson, Kimberley D. Bruce (114422), Bruce Kimberley D., Siow Richard C. M., Christopher D Byrne, Ethirajan, P., Priya Ethirajan (114421), Clough Geraldine F., Torrens, Christopher, Felino R A Cagampang, Giovanni E Mann, Hanson, Mark A., Christopher Torrens, Bruce, Kimberley D., Clough, Geraldine F., Siow, R.C., Cagampang, F.R.   +41 more
core   +1 more source