Results 141 to 150 of about 708,976 (400)

Genistein inhibits PDGF-stimulated proteoglycan synthesis in vascular smooth muscle without blocking PDGFß receptor phosphorylation [PDF]

, 2012
The signaling pathways that regulate the synthesis and structure of proteoglycans secreted by vascular smooth muscle cells are potential therapeutic targets for preventing lipid deposition in the early stage of atherosclerosis.
Ballinger, M, Getachew, R, Khachigian, L, LIAO, S, Little AM, P, Osman, N, Rezaei, H, Sanchez-Guerrero, E, Wang, H, Zheng, W   +9 more
core  

The influence of perfusion solution on renal graft viability assessment [PDF]

, 2012
BACKGROUND: Kidneys from donors after cardiac or circulatory death are exposed to extended periods of both warm ischemia and intra-arterial cooling before organ recovery.
CH Wilson, CH Wilson, D Shoskes, G Kootstra, JH Lee, JV Bonventre, JW Daemen, KJ Livak, MA Gok, MA Gok, MA Gok, MD Kay, MH Booster, MM El-Mas, MT Gravel, N Ahmad, N Ahmad, NR Brook, P Bell, RA Cowley, RT Currin, S Balupuri, SF Bronk, SR Johnson, TJ Wheatley, Y Lin, ZA Stewart   +26 more
core   +1 more source

Engineered MSC Aggregates with E/N‐Cadherin and IL‐6 Preconditioning for the Treatment of Systemic Sclerosis

Advanced Healthcare Materials, EarlyView.
Engineered 3D‐Cad/IL6‐MSC, developed through synergistic hE/N‐cad‐Fc and IL‐6 preconditioning, show remarkable therapeutic potential for systemic sclerosis. These engineered MSC aggregates reduce pathogenic inflammatory cell infiltration and restore immune balance among CD4+ T‐cell populations, offering a promising approach to optimize MSC based ...
Yue Zhang, Mengyuan Qian, Yirui Shi, Jiaxu Cao, Min Xu, Xin Wen, Yunxia Yan, Sha Liu, Hongwei Chen, Shanshan Liu, Jun Yang, Lingyun Sun   +11 more
wiley   +1 more source

THE EFFECT OF ANTI‐INFLAMMATORY DRUGS ON VASCULAR SMOOTH MUSCLE [PDF]

, 1967
B. J. Northover
openalex   +1 more source

Regulation of hypoxia-induced pulmonary hypertension by vascular smooth muscle hypoxia-inducible factor-1α.

American Journal of Respiratory and Critical Care Medicine, 2014
RATIONALE Chronic hypoxia induces pulmonary vascular remodeling, pulmonary hypertension, and right ventricular hypertrophy. At present, little is known about mechanisms driving these responses.
M. Ball, G. Waypa, Paul T. Mungai, Jacqueline M. Nielsen, Lyubov Czech, V. Dudley, Lauren Beussink, R. Dettman, S. Berkelhamer, R. Steinhorn, Sanjiv J. Shah, P. Schumacker   +11 more
semanticscholar   +1 more source

Conditioned Media from Mechanically Stimulated Macrophages Upregulate Osteogenic Genes in Human Mesenchymal Stromal Cells

Advanced Healthcare Materials, EarlyView.
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex, Ursula Menzel, Yann Ladner, Angela R. Armiento, Martin J. Stoddart   +4 more
wiley   +1 more source

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

Advanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz, Paulo Pereira, João Vasco Ferreira   +2 more
wiley   +1 more source

URETHANE AND CONTRACTION OF VASCULAR SMOOTH MUSCLE [PDF]

, 1979
Burton M. Altura, J. Weinberg
openalex   +1 more source

Biphasic Granular Bioinks for Biofabrication of High Cell Density Constructs for Dermal Regeneration

Advanced Healthcare Materials, EarlyView.
This study introduces a biphasic granular bioink (µInk) that enables 3D bioprinting of high cell density constructs for dermal regeneration. The bioink promotes cell proliferation, ECM deposition, and neovascularization, leading to tissue integration and reduced scar formation in vivo.
Rozalin Shamasha, Sneha Kollenchery Ramanathan, Kristin Oskarsdotter, Fatemeh Rasti Boroojeni, Aleksandra Zielińska, Sajjad Naeimipour, Philip Lifwergren, Nina Reustle, Lauren Roberts, Annika Starkenberg, Gunnar Kratz, Peter Apelgren, Karin Säljö, Jonathan Rakar, Lars Kölby, Daniel Aili, Johan Junker   +16 more
wiley   +1 more source

TOLMESOXIDE, A DRUG THAT LOWERS BLOOD PRESSURE BY A DIRECT RELAXANT EFFECT ON VASCULAR SMOOTH MUSCLE [PDF]

, 1978
John C. Doxey
openalex   +1 more source