Results 81 to 90 of about 202,203 (296)

A Vascular Microphysiological Model of Lung Fibrosis Reveals That Myofibroblasts and IPF Patient‐Derived Fibroblasts Impair Angiogenesis and Vasculogenesis

Advanced Functional Materials, EarlyView.
A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria, Adriana Blazeski, Eunkyung Clare Ko, Tran Thai, Shania Dantes, David A. Barbie, Sarah E. Shelton, Roger D. Kamm   +7 more
wiley   +1 more source

Generating Cell Surface Nucleated Hydrogels with an Artificial Membrane‐Binding Transglutaminase

Advanced Functional Materials, EarlyView.
Cell‐based therapies require advanced strategies to enhance cell delivery and bioactivity. Cell membrane engineering offers an avenue to impart new functions to delivered cells to boost their viability and function. Here, an artificial membrane‐binding transglutaminase is generated and biophysically characterized.
Rosalia Cuahtecontzi Delint, Tao Li, Kapil D. Patel, Will H. Zhang, Ben M. Carter, Graham J. Day, Adam W. Perriman   +6 more
wiley   +1 more source

Effect Of Mirthful Laughter On Vascular Function [PDF]

, 2010
In contrast to the well-established scientific evidence linking negative emotional states (e.g., depression, anxiety, or anger) to increased risk for cardiovascular disease, much less is known about the association between positive emotional states (e.g.,
Sugawara, Jun, Tanaka, Hirofumi, Tarumi, Takahashi   +2 more
core   +1 more source

Ultrasonographic vascular mechanics to assess arterial stiffness: a review [PDF]

European Heart Journal – Cardiovascular Imaging, 2015
In recent years, the role of arterial stiffness in the development of cardiovascular diseases has been explored more extensively. Local arterial stiffness may be gauged via ultrasound, measuring pulse transit time relative to changing vessel diameters and distending pressures. Recently, direct vessel-wall tracking systems have been devised based on new
Rogério, Teixeira, Maria João, Vieira, Alexandra, Gonçalves, Nuno, Cardim, Lino, Gonçalves   +4 more
openaire   +2 more sources

Endothelial Cells Angiogenesis in Sulfated Glycosaminoglycan (GAG) Hydrogels Enhanced by Bioactive Glass‐Released Ions

Advanced Functional Materials, EarlyView.
A mechanically tunable hydrogel composed of gelatin, chondroitin sulfate and laminin promotes angiogenesis in vitro without the supplement of growth factors. Endothelial cells morphogenesis was further enhanced by medium conditioned with bioactive glass 58S‐released ions (Ca and Si), thus offering a promising strategy to vascularize 3D tissue ...
Marco Piazzoni, Ilaria Borghi, Francesca Cadamuro, Sophia Dalfino, Riccardo Campanile, Sofia Nizzolo, Valeria Cassina, Francesca Tallia, Julian R. Jones, Francesco Mantegazza, Sabrina Bertini, Lorenzo Moroni, Francesco Nicotra, Laura Russo   +13 more
wiley   +1 more source

Arterial stiffness index as a marker for the occurrence of atherosclerotic cardiovascular disease

مجلة كلية الطب, 2016
Background: Arterial functional changes reflected by vascular stiffness might occur at early stages of cardiovascular disease before the morphological alterations reflected by increasing the intima media thickness and it is widely used as a very ...
Saba F. Salih, Najeeb H. Mohammed, Abbas N. Muslim, Sarab H. Al-Misebawi   +3 more
doaj   +1 more source

The Impact of Vein Mechanical Compliance on Arteriovenous Fistula Outcomes [PDF]

, 2016
© 2016 Elsevier Inc. Background Arteriovenous fistulae (AVFs) are the preferred access for hemodialysis but suffer a high early failure rate. The aim of this study was to determine how venous distensibility, as measured in vitro, relates to early ...
Barnes, Rachel, Barnes, Richard, Chetter, Ian C., Fagan, Michael, Smith, George E.   +4 more
core   +2 more sources

Interconnected Porous Hydrogels with Tunable Anisotropy Through Aqueous Emulsion Bioprinting

Advanced Functional Materials, EarlyView.
A 3D bioprintable microporous bioink is developed using an aqueous two‐phase system (ATPS) composed of extracellular matrix (ECM) mimetic biopolymers. The ATPS bioink enables the fabrication of interconnected porous architectures with up to 70% porosity, supporting long‐term cell viability and 3D cell alignment, enabling a simultaneous generation of ...
Hugo Edgar‐Vilar, Francisca P. Correia, Inês M. Freitas, Vítor M. Gaspar, João F. Mano   +4 more
wiley   +1 more source

Angiogenic and angiostatic factors in renal scleroderma-associated vasculopathy [PDF]

, 2017
BACKGROUND: The angiogenesis in systemic sclerosis (SSc) is impaired. An imbalance of pro-angiogenic factors and angiogenesis inhibitors has been implicated in the progression of peripheral microvascular damage, defective vascular repair and fibrosis ...
Afeltra, Antonella M. Vittoria, Amoroso, Antonio, Barbano, Biagio, Cianci, Rosario, Gigante, Antonietta, Margiotta, Domenico, Navarini, Luca, Rosato, Edoardo   +7 more
core   +1 more source

Circulating angiogenic cell populations, vascular function, and arterial stiffness [PDF]

Atherosclerosis, 2012
Several bone marrow-derived cell populations have been identified that may possess angiogenic activity and contribute to vascular homeostasis in experimental studies. We examined the extent to which lower quantities of these circulating angiogenic cell phenotypes may be related to impaired vascular function and greater arterial stiffness.We studied ...
Susan, Cheng, Na, Wang, Martin G, Larson, Joseph N, Palmisano, Gary F, Mitchell, Emelia J, Benjamin, Ramachandran S, Vasan, Daniel, Levy, Elizabeth L, McCabe, Joseph A, Vita, Thomas J, Wang, Stanley Y, Shaw, Kenneth S, Cohen, Naomi M, Hamburg   +13 more
openaire   +2 more sources