Results 71 to 80 of about 128,544 (288)

Abstract 377: Neonatal Hyperoxia Contributes To Early Cardio-renal Fibrosis And Systemic Vascular Stiffness In 1 Year Old Rats

, 2022
Background: There is a knowledge gap in the mechanisms linking neonatal hyperoxia (O 2 ) exposure and its contribution to cardio-renal dysfunction in adults born preterm.
Kulandavelu, Shathiyah, Chen, Pingping, DeFreitas, Marissa, Schmidt, Augusto, Benny, Merline, Wu, Shu, Tian, Runxia, Shelton, Elaine, Abitbol, Carolyn, Young, Karen   +9 more
core   +1 more source

Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng, Camila B. Tovani, Simona Bianco, Gianni Comandini, Aya Elghajiji, Mina Aleemardani, Roxana Moscalu, Jeremie Zappia, Bianca Fernandes, Olivia Annett, Chrissy L. Hammond, Jason Wong, Dave J. Adams, Fabrizio Scarpa, Michael R. Whitehouse, Annela M. Seddon, James P. K. Armstrong   +16 more
wiley   +1 more source

Effects of biomechanical and biochemical stimuli on angio- and vasculogenesis in a complex microvasculature-on-chip

iScience, 2023
Summary: The endothelium of blood vessels is a vital organ that reacts differently to subtle changes in stiffness and mechanical forces exerted on its environment (extracellular matrix (ECM)).
Dario Ferrari, Arunima Sengupta, Lyong Heo, Laszlo Pethö, Johann Michler, Thomas Geiser, Vinicio A. de Jesus Perez, Wolfgang M. Kuebler, Soheila Zeinali, Olivier T. Guenat   +9 more
doaj   +1 more source

Higher usual dietary intake of phytoestrogens is associated with lower aortic stiffness in postmenopausal women

, 2002
Objective¿ Phytoestrogens have been postulated to protect against cardiovascular diseases, but few studies have focused on the effect of Western dietary phytoestrogen intake.
Pijpelink, A, Bots, ML (Michiel), Grobbee, D.E., Lamberts, S.W.J., Schouw, Y.T., van der, Peeters, P.H.M., van der Schouw, YT, Bots, M.L., van Staveren, W.A., Peeters, PHM, Pijpe, A., van der Schouw, Y.T., Grobbee, DE, van Staveren, WA, Staveren, W.A., van, Lebrun, CEI (Corinne), Lebrun, C.E.I.   +16 more
core   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Effect of Fecal Microbiota Transplantation on Arterial Stiffness in Alcohol-Related Liver Cirrhosis: A Prospective Pilot Study

Life
Background: Alcohol-related liver disease is frequently associated with systemic vascular dysfunction and increased arterial stiffness. This may contribute to adverse clinical outcomes.
Cristian Ichim, Adrian Boicean, Romeo Mihaila, Samuel Bogdan Todor, Paula Anderco, Victoria Birlutiu   +5 more
doaj   +1 more source

A Novel Decellularized Fibrocartilage Graft Promotes Tympanic Membrane Repair

Advanced Healthcare Materials, EarlyView.
An off‐the‐shelf decellularized porcine meniscus fibrocartilage graft (MEND) is engineered for pediatric tympanoplasty. Featuring a microchannel architecture that promotes host cell invasion, MEND rapidly closes tympanic membrane perforations and fully remodels in vivo, outperforming fascia and matching cartilage grafts while avoiding donor‐site ...
Paul M. Gehret, Ryan M. Friedman, Gautham Nair, Stephanie L. Fung, Dana D. Ragbirsingh, John Germiller, Riccardo Gottardi   +6 more
wiley   +1 more source

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

Advanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones, Madeline Laude, Zeenat Oyebanji, Ruchi Birur, Andres Luengo Martinez, Isabelle Gilbert, Phillip Baek, Nichole Longbottom, Nicole McCullough, Staci J. Horn, Chien‐Yu Lin, Matthew J. Lohr, Fred Clubb, Manuel K. Rausch, Elizabeth Cosgriff‐Hernandez   +14 more
wiley   +1 more source

Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells

Advanced Healthcare Materials, EarlyView.
Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli, Arianna Iacomino, Federico Serpe, Lucia Iafrate, Marco Bastioli, Giorgia Montalbano, Michele D'Orazio, Biagio Palmisano, Silvia Franco, Arianna Mencattini, Roberta Angelini, Eugenio Martinelli, Alessandro Corsi, Mara Riminucci, Giancarlo Ruocco, Chiara Scognamiglio, Andrea Barbetta, Gianluca Cidonio   +17 more
wiley   +1 more source

Microglia mechanics : immune activation alters traction forces and durotaxis

, 2015
This work was supported by the Austrian Agency for International Cooperation in Education and Research (Scholarship to LB), Faculty of Computer Science and Biomedical Engineering at Graz University of Technology (Scholarship to LB), German National ...
Gather, M., Bollmann, Lars, Gather, Malte Christian, Kristian Franze, Gautier, H., Gerhard A. Holzapfel, Lars eBollmann, Giuliano Scarcelli, Shahapure, Rajesh, Malte C. Gather, Ulbricht, E., Rajesh Shahapure, Holzapfel, G., Gautier, Hélène O. B., Rajesh eShahapure, Bollmann, L., Franze, K., Elke eUlbricht, Scarcelli, Giuliano, Lars Bollmann, Scarcelli, G., Koser, David E., Ulbricht, Elke, David Elias Koser, Koser, D., David E. Koser, Kristian eFranze, Holzapfel, Gerhard A., Elke Ulbricht, Giuliano eScarcelli, Shahapure, R., Hélène O. B. Gautier, Franze, Kristian   +32 more
core   +1 more source