Results 81 to 90 of about 1,067,842 (374)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

EFFICACY OF THE ENDOVASCULAR TREATMENT OF THE THORACIC AND ABDOMINAL AORTIC ANEURYSMS IN CARTAGENA, COLOMBIA

Revista Ciencias Biomédicas, 2015
Introduction: The aortic aneurysms (AA) are a segmentary and permanent dilatation of the aorta that could end in a catastrophic outcome named acute aortic syndrome (AAS), which could curse with rupture and in most cases in death.
Marzola-Peña Katy, Arrieta-Usta Micaela
doaj  

Left Renal Vein Transection and Reconstruction for Functional Paraganglioma Resection: A Case Report

Vascular Specialist International
Paragangliomas are rare neuroendocrine tumors originating from extra-adrenal chromaffin cells and often require surgical management. We report the case of a 55-year-old male with a retroperitoneal paraganglioma diagnosed by imaging and elevated ...
Yeo-Jin Boo, Sang-Uk Han, Hoon Hur, Jun Bae Bang   +3 more
doaj   +1 more source

Experiences With Surgical Treatment of Chronic Lower Limb Ulcers at a Tertiary Hospital in Northwestern Tanzania: A Prospective Review of 300 Cases. [PDF]

, 2012
Chronic lower limb ulcers constitute a major public health problem of great important all over the world and contribute significantly to high morbidity and long-term disabilities. There is paucity of information regarding chronic lower limb ulcers in our
Chalya, Phillipo L, Gilyoma, Japhet M, Kidenya, Benson R, Mbunda, Fidelis, McHembe, Mabula D, Mshana, Stephen E, Rambau, Peter   +6 more
core   +3 more sources

Surgical Treatment of Buccofacial Region Vascular Anomalies Using an Intraoral Buccomucosal Flap Procedure [PDF]

Archives of Otolaryngology–Head & Neck Surgery, 2010
To report our experience in and our surgical technique of treating vascular anomalies of the buccofacial region using an intraoral buccomucosal flap approach.Retrospective medical record review and illustration of a specific surgical procedure.Academic tertiary care center.Thirty-two patients with vascular anomalies of the buccofacial region who have ...
Gregory M, Levitin, Stevan H, Thompson, Alejandro, Berenstein, Milton, Waner   +3 more
openaire   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Clavicular Chondrosarcoma: A Case Report and Brief Review of the Literature

International Journal of Hematology-Oncology and Stem Cell Research, 2016
Clavicular bone tumors occur in less than 0.5 percent of bone tumors. Primary chondrosarcoma is very rare even among clavicle tumors. The main symptom is a touchable mass in 69 % of patients.
Ali Ghorbani Abdehgah, Behnam Molavi, Saeed Reza Mehrpour, Amir Reza Radmard, Mohammad Mahjori, Nasser Kamalian, Hosein Kamranzadeh   +6 more
doaj  

History of the Innovation of Damage Control for Management of Trauma Patients: 1902-2016 [PDF]

, 2017
Objective: To review the history of the innovation of damage control (DC) for management of trauma patients. Background: DC is an important development in trauma care that provides a valuable case study in surgical innovation.
Ball, Chad G., Fabian, Timothy C., Feliciano, David V., Ivatury, Rao R., Kirkpatrick, Andrew W., Lucas, Charles E., Moore, Ernest E., Roberts, Derek J., Stelfox, Henry T., Zygun, David A.   +9 more
core   +3 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Incidence of wrong-site surgery list errors for a 2-year period in a single national health service board [PDF]

, 2017
Introduction: Wrong-site/side surgical "never events" continue to cause considerable harm to patients, healthcare professionals, and organizations within the United Kingdom.
Bowie, Paul, Ferguson, Lorna, Geraghty, Alistair, McIlhenny, Craig   +3 more
core   +1 more source