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Tissue Engineering and Regenerative Medicine, 2023
Polyethylene glycol (PEG) is a hydrophilic polymer, which has been known to have a neuroprotective effect by sealing the ruptured cell membrane, but PEG effects on the vascular systems and its underlying mechanisms remain unclear. Here, we showed the neuroprotective effect of PEG by preventing damage to the vascular system.A spinal contusion was made ...
Jinseung Lee +4 more
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Polyethylene glycol (PEG) is a hydrophilic polymer, which has been known to have a neuroprotective effect by sealing the ruptured cell membrane, but PEG effects on the vascular systems and its underlying mechanisms remain unclear. Here, we showed the neuroprotective effect of PEG by preventing damage to the vascular system.A spinal contusion was made ...
Jinseung Lee +4 more
openaire +2 more sources
Vascular Aspects and Hemodynamic Consequences of Central Nervous System Injury
Central Nervous System Trauma, 1986We document here microvascular alterations occurring in models of mild, moderate, and severe cerebral ischemic injury. The relationship of the vascular abnormalities to the generation of hemodynamic alterations was also evaluated. Following periods of severe incomplete ischemia, scanning electron microscopic analysis of cerebral microvessels revealed ...
W D, Dietrich +4 more
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Innate and Innate-Like Immune System in Hypertension and Vascular Injury
Current Hypertension Reports, 2019To describe the important role played by innate and innate-like immunity in the pathophysiology of hypertension and vascular injury.Innate immune cells, such as neutrophils, dendritic cells, myeloid-derived suppressor cells, and monocytes/macrophages and innate lymphoid cells such as natural killer cells and unconventional T lymphocytes like γδ T cells
Akinori, Higaki +3 more
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Radiographics, 2020
Radiation therapy (RT) continues to play a central role as an effective therapeutic modality for a variety of tumors and vascular malformations in the central nervous system.
M. Katsura +5 more
semanticscholar +1 more source
Radiation therapy (RT) continues to play a central role as an effective therapeutic modality for a variety of tumors and vascular malformations in the central nervous system.
M. Katsura +5 more
semanticscholar +1 more source
In vitro models to evaluate acute and chronic injury to the heart and vascular systems
Toxicology in Vitro, 2005Multiple in vitro model systems are currently available to evaluate structure and function relationships in the cardiovascular system as well as the system's response to injury. As the level of molecular sophistication continues to advance, so does the level of complexity of the analysis.
Charles R, Partridge +2 more
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Vascular injury in systemic sclerosis: Angiotensin-converting enzyme insertion/deletion polymorphism
Current Rheumatology Reports, 2004The microvascular involvement in systemic sclerosis (SSc) is characterized by endothelial damage and smooth muscle cell migration in the intima. The vascular pathologic modifications in SSc are strikingly similar to those of atherosclerosis. SSc also is characterized by an accelerated macrovascular disease.
FATINI, CINZIA +3 more
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Circulating endothelial cells and vascular injury in systemic lupus erythematosus
Current Rheumatology Reports, 2000In flares of systemic lupus erythematosus (SLE), endothelial cells activated by immune stimuli are potential participants in the inflammatory processes, which contribute to injury. Elevated levels of circulating endothelial cells (CEC) may be a proxy for vascular injury, as demonstrated in patients with sickle cell anemia during acute crises. In active
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A collaborative research system for functional outcomes following wartime extremity vascular injury
Journal of Trauma and Acute Care Surgery, 2012Abstract : Vascular injury with hemorrhage and ischemia is a significant cause of battlefield morbidity (i.e., amputation) and mortality. Recent reports have demonstrated the rate of vascular injury in modern combat to be five times that reported in previous wars.
Adam, Stannard +8 more
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Pulmonary vascular injury in systemic sclerosis: Diagnosis and treatment
2021Systemic sclerosis is a chronic disorder characterized by vascular damage, immune dysregulation and fibrosis. Pulmonary manifestations of scleroderma include pulmonary hypertension with or without interstitial lung disease. Systemic sclerosis patients who develop pulmonary hypertension report dyspnea and functional limitation and have right and left ...
Puppo F., Negrini S., Carbone R. G.
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The Xylum clot signature analyzer®: A dynamic flow system that simulates vascular injury
Thrombosis Research, 1998The Xylum Clot Signature Analyzer (CSA) is an automated, user-friendly, benchtop analyzer that assesses platelet function and coagulation in non-anticoagulated whole blood under physiological flow and temperature conditions. From blood drawn in a single venipuncture, the CSA measures: a) the time for platelets to occlude holes "punched" in a blood ...
C K, Li +4 more
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