Results 121 to 130 of about 173,434 (149)

Tissue engineering in the vascular graft

Cytotechnology, 1992
[on SciFinder (R)]
Massia, S. P., Hubbell, J. A.
openaire   +2 more sources

Development of Tissue Engineered Vascular Grafts

Current Pharmaceutical Biotechnology, 2007
Vascular bypass grafting is a commonly performed procedure for ischemic heart disease and peripheral vascular disease. However, approximately one in fourteen patients do not have suitable autologous arteries or veins available for grafting. Synthetic vascular grafts were introduced in the 1960s to overcome these problems, but while they perform ...
Campbell, G. R., Campbell, J. H.
openaire   +5 more sources

Vascularization—The Conduit to Viable Engineered Tissues

Tissue Engineering Part B: Reviews, 2009
Long-term viability of thick three-dimensional engineered tissue constructs is a major challenge. Addressing it requires development of vessel-like network that will allow the survival of the construct in vitro and its integration in vivo owing to improved vascularization after implantation.
Tamar, Kaully, Keren, Kaufman-Francis, Ayelet, Lesman, Shulamit, Levenberg   +3 more
openaire   +2 more sources

Engineering vascularized tissue

Nature Biotechnology, 2005
The creation in vitro of vascularized skeletal muscle represents a first step to the engineering of more complex tissue architectures.
Rakesh K Jain, Patrick Au, Josh Tam, Dan G Duda, Dai Fukumura   +4 more
openaire   +1 more source

Microfluidic vascular-bed devices for vascularized 3D tissue engineering: tissue engineering on a chip

Biomedical Microdevices, 2019
In this report, we describe a microfluidic vascular-bed (micro-VB) device providing a platform for 3D tissue engineering with vascular network formation. The micro-VB device allows functional connections between endothelial capillaries of heterogeneous sections (5-100 μm in diameter) and artificial plastic tubes or reservoirs (1-10 mm in diameter ...
Hiroaki, Takehara, Katsuhisa, Sakaguchi, Hidekazu, Sekine, Teruo, Okano, Tatsuya, Shimizu   +4 more
openaire   +2 more sources

Vascularization in Craniofacial Bone Tissue Engineering

Journal of Dental Research, 2018
Craniofacial bones, separate from the appendicular skeleton, bear a significant amount of strain and stress generated from mastication-related muscles. Current research on the regeneration of craniofacial bone focuses on the reestablishment of an elaborate vascular network.
T. Tian, T. Zhang, Y. Lin, X. Cai
openaire   +2 more sources

Tissue engineered prefabricated vascularized flaps

Head & Neck, 2007
AbstractBackground.Microvascular free tissue transfer has become increasingly popular in the reconstruction of head and neck defects, but it also has its disadvantages. Tissue engineering allows the generation of neo‐tissue for implantation, but these tissues are often avascular.
Oo, Kenneth Kian Kwan, Ong, Wei Chen, Ang, Annette Hui Chi, Hutmacher, Dietmar, Tan, Luke Kim Siang   +4 more
openaire   +3 more sources

Vascular tissue engineering: the next generation

Trends in Molecular Medicine, 2012
It is the ultimate goal of tissue engineering: an autologous tissue engineered vascular graft (TEVG) that is immunologically compatible, nonthrombogenic, and can grow and remodel. Currently, native vessels are the preferred vascular conduit for procedures such as coronary artery bypass (CABG) or peripheral bypass surgery.
Muriel A, Cleary, Erik, Geiger, Conor, Grady, Cameron, Best, Yuji, Naito, Christopher, Breuer   +5 more
openaire   +2 more sources

Engineering vascularized skeletal muscle tissue

Nature Biotechnology, 2005
One of the major obstacles in engineering thick, complex tissues such as muscle is the need to vascularize the tissue in vitro. Vascularization in vitro could maintain cell viability during tissue growth, induce structural organization and promote vascularization upon implantation.
Levenberg, Shulamit, Rouwkema, Jeroen, Macdonald, Mara, Garfein, Evan S., Kohane, Daniel S., Darland, Diane C., Marini, Robert, van Blitterswijk, Clemens, Mulligan, Richard C., D'Amore, Patricia A., Langer, Robert   +10 more
openaire   +3 more sources

Vascular Assembly in Natural and Engineered Tissues

Annals of the New York Academy of Sciences, 2002
Abstract: With the advent of molecular embryology and exploitation of genetic models systems, many genes necessary for normal blood vessel formation during early development have been identified. These genes include soluble effectors and their receptors, as well as components of cell‐cell junctions and mediators of cell‐matrix interactions.
Karen K, Hirschi, Thomas C, Skalak, Shayn M, Peirce, Charles D, Little   +3 more
openaire   +2 more sources