Results 161 to 170 of about 1,741 (203)

The Advent of Vascularized Composite Allotransplantation

Clinics in Plastic Surgery, 2017
Modern microsurgical techniques have made possible a broad spectrum of novel means for the reconstruction of complex bone and soft tissue defects. These techniques, in combination with developments in transplant immunology, have led to successful hand and facial allotransplantation and achievement of the highest rung in the reconstructive ladder ...
Curtis L, Cetrulo, Zhi Yang, Ng, Jonathan M, Winograd, Kyle R, Eberlin   +3 more
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Pediatric Vascularized Composite Allotransplantation

Annals of Plastic Surgery, 2014
Vascularized composite allotransplantation (VCA) has experienced a growing acceptance, which has led to a debate centered on extending the indications of the procedure to include pediatric patients. The aim of this article was to discuss such indications based on the evidence in pediatric solid organ transplantation, reconstructive surgery in children,
Gaby, Doumit, Bahar Bassiri, Gharb, Antonio, Rampazzo, Francis, Papay, Maria Z, Siemionow, James E, Zins   +5 more
openaire   +2 more sources

Vascularized Composite Allotransplantation at a Crossroad

Transplantation Proceedings, 2011
Vascularized composite allotransplantation is a relatively young field that has shown significant growth in the past decade. The subspecialty offers opportunities that are not available with solid organ transplants. However, the field also faces significant hurdles in increasing clinical volumes.
K V, Ravindra, H, Xu, S T, Ildstad
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Vascularized composite allotransplantation

2021
Abstract Vascularized composite allotransplants contain the products of multiple cell lineages to reconstruct the form and function of complex, composite tissue defects. This chapter discusses the ethical principles and the immunology behind composite transplantation, including the selection of immunomodulatory agents and the immune ...
Daniel Wilks, Simon Kay
openaire   +1 more source

Genitourinary vascularized composite allotransplantation

Current Opinion in Organ Transplantation, 2017
Genitourinary vascularized allotransplantation (GUVCA) is gaining interest as a treatment option for patients with functional and aesthetic urogenital tissue loss. Only three cases have been done worldwide and research on the implementation and feasibility of this procedure is in an elementary state.The psychosocial impact and ethical considerations ...
Ilse M, Schol, Dicken S C, Ko, Curtis L, Cetrulo   +2 more
openaire   +2 more sources

Vascularized Composite Allotransplantation

Transplantation, 2012
The definition of vascularized composite allograft (VCA) and the nomenclature require further attention and interaction with the competent authorities. When compared with solid organ transplantation, VCA donation and allocation imply additional elements such as donor identification, race, and bone constitution, which need to be worked into a scheme for
Stefan, Schneeberger, Emmanuel, Morelon, Luis, Landin   +2 more
openaire   +2 more sources

Vascularized Composite Allotransplantation

2020
Vascularized composite tissue allotransplantation (VCA) is the youngest field in organ transplantation and refers to the transplantation of anatomical structures with multiple tissue types. VCA has significantly expanded the surgical armamentarium and has enabled the reconstruction and restoration of body parts after devastating trauma, amputation ...
Georgios Vrakas, Annemarie Weissenbacher, Henk Giele   +2 more
openaire   +1 more source

Vascularized Composite Allotransplantation of the Hand

Annals of Plastic Surgery, 2023
Background Hand transplantation (HT) has emerged as an intervention of last resort for those who endured amputation or irreparable loss of upper extremity function. However, because of the considerable effort required for allograft management and the risks of lifelong immunosuppression, patient eligibility is critical to ...
Matteo, Laspro, Ogechukwu C, Onuh, Kassandra, Carrion, Hilliard T, Brydges, David L, Tran, Bachar F, Chaya, Augustus, Parker, Vishal D, Thanik, Sheel, Sharma, Eduardo D, Rodriguez   +9 more
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Acute rejection in vascularized composite allotransplantation

Current Opinion in Organ Transplantation, 2014
Acute rejection is the most common complication after vascularized composite allotransplantation (VCA). This review provides a state-of-the-art analysis of prevention, diagnosis and treatment of acute rejection episodes and highlights recent findings with the potential to improve patient care and enhance understanding of the underlying biologic ...
Sebastian, Fischer, Christine G, Lian, Maximilian, Kueckelhaus, Terry B, Strom, Elazer R, Edelman, Rachel A, Clark, George F, Murphy, Anil K, Chandraker, Leonardo V, Riella, Stefan G, Tullius, Bohdan, Pomahac   +10 more
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Current Status of Vascularized Composite Allotransplantation

The American Surgeon™, 2019
The field of vascularized composite allotransplantation (VCA) has moved from a highly experimental procedure to, at least for some patients, one of the best treatment alternatives for catastrophic tissue loss or dysfunction. Although the worldwide experience is still limited, progress has been made in translation to the clinic, and hand transplantation
Christina L, Kaufman, Neal, Bhutiani, Allan, Ramirez, Huey Y, Tien, Michelle D, Palazzo, Elkin, Galvis, Scott, Farner, Tuna, Ozyurekoglu, Christopher M, Jones   +8 more
openaire   +2 more sources