Results 11 to 20 of about 273,619 (385)

EULAR recommendations for the management of ANCA-associated vasculitis: 2022 update

Annals of the Rheumatic Diseases, 2023
Background Since the publication of the EULAR recommendations for the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in 2016, several randomised clinical trials have been published that have the potential to change ...
B. Hellmich, B. Sánchez-Álamo, J. Schirmer, A. Berti, D. Blockmans, M. Cid, Julia U. Holle, Nicole Hollinger, O. Karadag, A. Kronbichler, M. Little, R. Luqmani, A. Mahr, P. Merkel, A. Mohammad, S. Monti, C. Mukhtyar, J. Musial, F. Price-Kuehne, M. Segelmark, Y. K. O. Teng, B. Terrier, G. Tómasson, A. Vaglio, D. Vassilopoulos, P. Verhoeven, D. Jayne   +26 more
semanticscholar   +1 more source

2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Antineutrophil Cytoplasmic Antibody–Associated Vasculitis

Arthritis care & research, 2021
To provide evidence‐based recommendations and expert guidance for the management of antineutrophil cytoplasmic antibody–associated vasculitis (AAV), including granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and eosinophilic ...
Sharon A. Chung, C. Langford, M. Maz, A. Abril, M. Gorelik, G. Guyatt, A. Archer, D. Conn, Kathy A Full, P. Grayson, M. Ibarra, L. Imundo, Susan Kim, P. Merkel, Rennie L. Rhee, P. Seo, J. Stone, S. Sule, R. Sundel, Omar I Vitobaldi, A. Warner, K. Byram, A. Dua, Nedaa M Husainat, K. James, Mohamad A. Kalot, Y. C. Lin, J. Springer, Marat Turgunbaev, A. Villa-Forte, Amy S. Turner, R. Mustafa   +31 more
semanticscholar   +2 more sources

2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Giant Cell Arteritis and Takayasu Arteritis

Arthritis & Rheumatology, 2021
To provide evidence‐based recommendations and expert guidance for the management of giant cell arteritis (GCA) and Takayasu arteritis (TAK) as exemplars of large vessel vasculitis.
M. Maz, Sharon A. Chung, A. Abril, C. Langford, M. Gorelik, G. Guyatt, A. Archer, D. Conn, Kathy A Full, P. Grayson, M. Ibarra, L. Imundo, Susan Kim, P. Merkel, Rennie L. Rhee, P. Seo, J. Stone, S. Sule, R. Sundel, Omar I Vitobaldi, A. Warner, K. Byram, A. Dua, Nedaa M Husainat, K. James, Mohamad A. Kalot, Y. C. Lin, J. Springer, Marat Turgunbaev, A. Villa-Forte, Amy S. Turner, R. Mustafa   +31 more
semanticscholar   +1 more source

Avacopan for the Treatment of ANCA-Associated Vasculitis.

New England Journal of Medicine, 2021
BACKGROUND The C5a receptor inhibitor avacopan is being studied for the treatment of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. METHODS In this randomized, controlled trial, we assigned patients with ANCA-associated vasculitis in
D. Jayne, P. Merkel, Tom Schall, P. Bekker   +3 more
semanticscholar   +2 more sources

Inflammatory vaginitis in women on long-term rituximab treatment for autoimmune disorders

BMC Women's Health, 2021
Background Consequences of long-term B cell depletion with rituximab are not well understood. We describe inflammatory vaginitis as a potential side effect of long-term rituximab treatment, distinct from previously described vulvovaginal pyoderma ...
Laura Yockey, Sarah Dowst, Reza Zonozi, Noah Huizenga, Patrick Murphy, Karen Laliberte, Jillian Rosenthal, John L. Niles, Caroline M. Mitchell   +8 more
doaj   +1 more source

Diagnostic delays in vasculitis and factors associated with time to diagnosis

Orphanet Journal of Rare Diseases, 2021
Background Patients with vasculitis, a set of rare diseases, encounter delays in obtaining an accurate diagnosis which can lead to substantial morbidity and increased mortality.
Antoine G. Sreih, Keri Cronin, Dianne G. Shaw, Kalen Young, Cristina Burroughs, Joyce Kullman, Kirthi Machireddy, Carol A. McAlear, Peter A. Merkel, for the Vasculitis Patient-Powered Research Network   +9 more
doaj   +1 more source

Global epidemiology of vasculitis

Nature Reviews Rheumatology, 2021
The many forms of vasculitis are characterized by inflammation of blood vessels, leading to potentially long-term sequelae including vision loss, aneurysm formation and kidney failure. Accurate estimation of the incidence and prevalence has been hampered
R. Watts, G. Hatemi, J. Burns, A. Mohammad   +3 more
semanticscholar   +1 more source

A sore red eye with systemic involvement [PDF]

, 2012
The study of happiness has long been a playground for philosophical speculation. By lack of empirical measures of happiness, it was not possible to check propositions about the matter.
Lightman, SL, Pusey, CD, Shalchi, Z, Taylor, SRJ   +3 more
core   +2 more sources

Giant Cell Arteritis Refractory to Interleukin-6 and Interleukin-17 Inhibition Treated With Upadacitinib. [PDF]

ACR Open Rheumatol
Giant cell arteritis (GCA) is a granulomatous vasculitis that can involve both cranial and extracranial vessels. Although interleukin‐6 (IL‐6) receptor blockade is an established therapy, treatment options for medically refractory disease remain limited.
Vest LS, Ahmad A, Valasareddy S, Phillips N, Kilian A.   +4 more
europepmc   +2 more sources

A randomised study of rituximab and belimumab sequential therapy in PR3 ANCA-associated vasculitis (COMBIVAS): design of the study protocol

Trials, 2023
Background Sequential B cell-targeted immunotherapy with BAFF antagonism (belimumab) and B cell depletion (rituximab) may enhance B cell targeting in ANCA-associated vasculitis (AAV) through several mechanisms.
Mark E. McClure, Seerapani Gopaluni, James Wason, Robert B. Henderson, Andre Van Maurik, Caroline C.O. Savage, Charles D. Pusey, Alan D. Salama, Paul A. Lyons, Jacinta Lee, Kim Mynard, David R. Jayne, Rachel B. Jones, on behalf the COMBIVAS investigators   +13 more
doaj   +1 more source