Results 21 to 30 of about 160,652 (313)

Efficacy and safety of rituximab in the treatment of eosinophilic granulomatosis with polyangiitis

RMD Open, 2019
Introduction Eosinophilic granulomatosis with polyangiitis (EGPA) is a subset of antineutrophil cytoplasmic antibodies (ANCA) associated vasculitis with distinct pathophysiological mechanisms, clinical features and treatment responses.
David Jayne, Rachel B Jones, Vítor Teixeira, Aladdin J Mohammad, Rona Smith   +4 more
doaj   +1 more source

Rituximab Associated Hypogammaglobulinemia in Autoimmune Disease

Frontiers in Immunology, 2021
ObjectiveTo evaluate the characteristics of patients with autoimmune disease with hypogammaglobulinemia following rituximab (RTX) and describe their long-term outcomes, including those who commenced immunoglobulin replacement therapy.MethodsPatients ...
Joanna Tieu, Joanna Tieu, Joanna Tieu, Rona M. Smith, Rona M. Smith, Seerapani Gopaluni, Seerapani Gopaluni, Dinakantha S. Kumararatne, Mark McClure, Mark McClure, Ania Manson, Sally Houghton, David R. W. Jayne, David R. W. Jayne   +13 more
doaj   +1 more source

Takayasu arteritis in childhood: retrospective experience from a tertiary referral centre in the United Kingdom. [PDF]

, 2015
Takayasu arteritis (TA) is an idiopathic large-vessel vasculitis affecting the aorta and its major branches. Although the disease rarely affects children, it does occur, even in infants.
McMahon, AM, Paul A Brogan, Pavla Dolezalova, Giulia Varnier, Despina Eleftheriou, Eleftheriou, D, Varnier, G, Muthana Al-Obaidi, Al-Obaidi, M, Dolezalova, P, Brogan, PA, Anne-Marie McMahon   +11 more
core   +1 more source

Highly Sensitive Flow Cytometric Detection of Residual B-Cells After Rituximab in Anti-Neutrophil Cytoplasmic Antibodies-Associated Vasculitis Patients

Frontiers in Immunology, 2020
BackgroundB-cell depletion with rituximab (RTX) is an effective treatment for anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) patients.
Laura S. van Dam, Jelle M. Oskam, Sylvia W. A. Kamerling, Eline J. Arends, O. W. Bredewold, Magdalena A. Berkowska, Jacques J. M. van Dongen, Ton J. Rabelink, Cees van Kooten, Y. K. Onno Teng   +9 more
doaj   +1 more source

Efficacy of belimumab combined with rituximab in severe systemic lupus erythematosus: study protocol for the phase 3, multicenter, randomized, open-label Synbiose 2 trial

Trials, 2022
Background Belimumab, an anti-B-cell activating factor antibody, is approved for the treatment of auto-antibody positive systemic lupus erythematosus with a high degree of disease activity.
Mieke van Schaik, Eline J. Arends, Darius Soonawala, Ellen van Ommen, Karina de Leeuw, Maarten Limper, Pieter van Paassen, Tom W. J. Huizinga, René E. M. Toes, Cees van Kooten, Joris I. Rotmans, Ton J. Rabelink, Y. K. Onno Teng   +12 more
doaj   +1 more source

Granulomatous vasculitis: an unusual renal vasculitis [PDF]

Nephrology Dialysis Transplantation, 1999
cyclophosphamide; idiopathic granulomat- response. A few granulomata were seen in the inter-ous vasculitis; visceral giant-cell arteritis stitium. The glomeruli showed secondary ischaemicchanges, but no primary glomerulonephritis and noimmunoglobulin deposits.The skin biopsy showed similar changes of a leuko-
S J, Hailwood, D G, Scott, T H, Barker, A, Heaton   +3 more
openaire   +2 more sources

Leukocytoclastic Vasculitis after Pneumococcal pneumonia in an Elderly Adult [PDF]

, 2007
Hypersensitivity vasculitis (HSV) has been used to describe several forms of vasculitis of small blood vessels, including Henoch-Sch?nlein purpura (HSP), mixed cryoglobulinemia, and allergic vasculitis, etc.
Mizuta, Yohei, Yanagihara, Katsunori, Miyazaki, Yoshitsugu, Kohno, Shigeru, Nakamura, Shigeki, Izumikawa, Koichi, Soejima, Yoshifumi, Hirakata, Yoichi, Seki, Masafumi   +8 more
core   +1 more source

Effects of the COVID‐19 Pandemic on Patients Living With Vasculitis

, 2020
This study aimed to analyze the concerns and health‐related behaviors in patients with vasculitis during the early phase of the coronavirus disease 2019 (COVID‐19) pandemic in North America.
W. Benjamin Nowell, Curtis, Jeffrey R., Peter A. Merkel, Jeffrey R. Curtis, George, Michael, Young, Kalen, Joyce Kullman, Curtis, David, Ferrada, Marcela, Gordon, Jennifer, Jennifer Gordon, Banerjee, Shubhasree, Shaw, Dianne G., Maria I. Danila, Kelly Gavigan, Kalen Young, Shilpa Venkatachalam, Kullman, Joyce, Burroughs, Cristina, Grayson, Peter C., Peter C. Grayson, Nowell, W. Benjamin, Michael George, Merkel, Peter A., Shubhasree Banerjee, David Curtis, Marcela Ferrada, Cristina Burroughs, Venkatachalam, Shilpa, Gavigan, Kelly, Danila, Maria I., Dianne G. Shaw   +31 more
core   +1 more source

Is There a Role for TNFα Blockade In ANCA-Associated Vasculitis and Glomerulonephritis? [PDF]

, 2016
Tumour necrosis factor alpha (TNFα) is a cytokine which is pivotal in the inflammatory response. Blockade of TNFα has been shown to be effective in a number of human autoimmune diseases, including rheumatoid arthritis, raising the question whether this ...
Pusey, CD, McAdoo, SP
core   +1 more source

A review of studies of the proteomes of circulating microparticles: key roles for galectin-3-binding protein-expressing microparticles in vascular diseases and systemic lupus erythematosus

Clinical Proteomics, 2017
Subcellular microvesicles (MVs) have attracted increasing interest during the past decades. While initially considered as inert cellular debris, several important roles for MVs in physiological homeostasis, cancer, cardiovascular, and autoimmune diseases
Christoffer T. Nielsen, Ole Østergaard, Niclas S. Rasmussen, Søren Jacobsen, Niels H. H. Heegaard   +4 more
doaj   +1 more source