Results 11 to 20 of about 166,248 (313)

[Primary CNS Vasculitis - An Overview].

, 2022
Primary CNS Vasculitis - An Overview Abstract. Cerebral vasculitis, especially the primary vasculitis of the central nervous systems (primary CNS vasculitis), are rare inflammatory diseases of the small- and medium-sized vessels of the CNS.
Kamber, Nicole, Hammer, Helly, Chan, Andrew, Diem, Lara, Salmen, Anke, Hoepner, Robert, Friedli, Christoph, Helly Hammer, Robert Hoepner, Nicole Kamber, Andrew Chan, Christoph Friedli, Anke Salmen, Lara Diem   +13 more
core   +1 more source

Efficacy and safety of rituximab in the treatment of eosinophilic granulomatosis with polyangiitis

RMD Open, 2019
Introduction Eosinophilic granulomatosis with polyangiitis (EGPA) is a subset of antineutrophil cytoplasmic antibodies (ANCA) associated vasculitis with distinct pathophysiological mechanisms, clinical features and treatment responses.
David Jayne, Rachel B Jones, Vítor Teixeira, Aladdin J Mohammad, Rona Smith   +4 more
doaj   +1 more source

Highly Sensitive Flow Cytometric Detection of Residual B-Cells After Rituximab in Anti-Neutrophil Cytoplasmic Antibodies-Associated Vasculitis Patients

Frontiers in Immunology, 2020
BackgroundB-cell depletion with rituximab (RTX) is an effective treatment for anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) patients.
Laura S. van Dam, Jelle M. Oskam, Sylvia W. A. Kamerling, Eline J. Arends, O. W. Bredewold, Magdalena A. Berkowska, Jacques J. M. van Dongen, Ton J. Rabelink, Cees van Kooten, Y. K. Onno Teng   +9 more
doaj   +1 more source

Rituximab Associated Hypogammaglobulinemia in Autoimmune Disease

Frontiers in Immunology, 2021
ObjectiveTo evaluate the characteristics of patients with autoimmune disease with hypogammaglobulinemia following rituximab (RTX) and describe their long-term outcomes, including those who commenced immunoglobulin replacement therapy.MethodsPatients ...
Joanna Tieu, Joanna Tieu, Joanna Tieu, Rona M. Smith, Rona M. Smith, Seerapani Gopaluni, Seerapani Gopaluni, Dinakantha S. Kumararatne, Mark McClure, Mark McClure, Ania Manson, Sally Houghton, David R. W. Jayne, David R. W. Jayne   +13 more
doaj   +1 more source

Efficacy of belimumab combined with rituximab in severe systemic lupus erythematosus: study protocol for the phase 3, multicenter, randomized, open-label Synbiose 2 trial

Trials, 2022
Background Belimumab, an anti-B-cell activating factor antibody, is approved for the treatment of auto-antibody positive systemic lupus erythematosus with a high degree of disease activity.
Mieke van Schaik, Eline J. Arends, Darius Soonawala, Ellen van Ommen, Karina de Leeuw, Maarten Limper, Pieter van Paassen, Tom W. J. Huizinga, René E. M. Toes, Cees van Kooten, Joris I. Rotmans, Ton J. Rabelink, Y. K. Onno Teng   +12 more
doaj   +1 more source

[Cocaine-induced vasculitis and mimics of vasculitis]. [PDF]

, 2022
Cocaine is a psychotropic tropane alkaloid and stimulant drug. Nasal insufflation of cocaine powder is a common route of administration. In Germany, cocaine is frequently adulterated with levamisole, an anthelminthic drug with immunomodulatory effects ...
Holl-Ulrich, Konstanze, Krusche, Martin, Kötter, Ina, Lötscher, Fabian, Ruffer, Nikolas, Nikolas Ruffer, Martin Krusche, Fabian Lötscher, Ina Kötter, Konstanze Holl-Ulrich   +9 more
core   +1 more source

Granulomatous vasculitis: an unusual renal vasculitis [PDF]

Nephrology Dialysis Transplantation, 1999
cyclophosphamide; idiopathic granulomat- response. A few granulomata were seen in the inter-ous vasculitis; visceral giant-cell arteritis stitium. The glomeruli showed secondary ischaemicchanges, but no primary glomerulonephritis and noimmunoglobulin deposits.The skin biopsy showed similar changes of a leuko-
S J, Hailwood, D G, Scott, T H, Barker, A, Heaton   +3 more
openaire   +2 more sources

Effects of the COVID‐19 Pandemic on Patients Living With Vasculitis

, 2020
This study aimed to analyze the concerns and health‐related behaviors in patients with vasculitis during the early phase of the coronavirus disease 2019 (COVID‐19) pandemic in North America.
W. Benjamin Nowell, Curtis, Jeffrey R., Peter A. Merkel, Jeffrey R. Curtis, George, Michael, Young, Kalen, Joyce Kullman, Curtis, David, Ferrada, Marcela, Gordon, Jennifer, Jennifer Gordon, Banerjee, Shubhasree, Shaw, Dianne G., Maria I. Danila, Kelly Gavigan, Kalen Young, Shilpa Venkatachalam, Kullman, Joyce, Burroughs, Cristina, Grayson, Peter C., Peter C. Grayson, Nowell, W. Benjamin, Michael George, Merkel, Peter A., Shubhasree Banerjee, David Curtis, Marcela Ferrada, Cristina Burroughs, Venkatachalam, Shilpa, Gavigan, Kelly, Danila, Maria I., Dianne G. Shaw   +31 more
core   +1 more source

A review of studies of the proteomes of circulating microparticles: key roles for galectin-3-binding protein-expressing microparticles in vascular diseases and systemic lupus erythematosus

Clinical Proteomics, 2017
Subcellular microvesicles (MVs) have attracted increasing interest during the past decades. While initially considered as inert cellular debris, several important roles for MVs in physiological homeostasis, cancer, cardiovascular, and autoimmune diseases
Christoffer T. Nielsen, Ole Østergaard, Niclas S. Rasmussen, Søren Jacobsen, Niels H. H. Heegaard   +4 more
doaj   +1 more source

Is There a Role for TNFα Blockade In ANCA-Associated Vasculitis and Glomerulonephritis? [PDF]

, 2016
Tumour necrosis factor alpha (TNFα) is a cytokine which is pivotal in the inflammatory response. Blockade of TNFα has been shown to be effective in a number of human autoimmune diseases, including rheumatoid arthritis, raising the question whether this ...
Pusey, CD, McAdoo, SP, Charles D Pusey, Stephen P McAdoo   +3 more
core   +1 more source