Results 181 to 190 of about 184,374 (299)

Comparative Pharmacokinetics of Intranasal or Intramuscular Atipamezole in Unsedated Dogs and Efficacy for Reversal of Xylazine Sedation

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The objectives of this study were to evaluate ATIP pharmacokinetics (PK) in healthy Beagle dogs after IM and IN dosing (Phase I), and to compare the rate of reversal of IM versus IN routes for xylazine (XYL) sedation (Phase II). This study was comprised of two sequential, randomized, crossover experiments. The initial PK study dosed ATIP by IN
Vanessa E. Cowan   +7 more
wiley   +1 more source

Excessive hypercholesterolemia in pregnancy impairs the cardiovascular health of the adult female and male offspring. [PDF]

open access: yesBiosci Rep
Graton ME   +7 more
europepmc   +1 more source

Exposure to Subcutaneously Administered Butorphanol in Horses Pre‐Treated With Detomidine or Detomidine‐Vatinoxan

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The aim of the study was to determine the exposure to subcutaneously administered butorphanol in horses pre‐treated with intravenous (IV) detomidine, with or without vatinoxan, a peripherally selective alpha2‐adrenoceptor antagonist. Five healthy, adult horses received three IV treatments 7 days apart, in a randomized, cross‐over design ...
Juhana M. Honkavaara   +5 more
wiley   +1 more source

Pharmacokinetics of Long‐Acting Ampicillin and Its Impact on the Gut Microbiome and Resistome in Rhesus Macaques (Macaca mulatta)

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Injectable antimicrobials with documented prolonged dosing intervals (> 48 h) for use in rhesus macaques are sparse. The objective of our study was to assess the pharmacokinetics, urine excretion, and effects on gut microbiome and resistome of intramuscular administered long‐acting formulation of ampicillin (Albipen LA) in macaques.
Annemiek Maaskant   +9 more
wiley   +1 more source

Corrigendum: Current Knowledge on the Vascular Effects of Menthol

open access: yesFrontiers in Physiology, 2020
Henrique Silva   +3 more
doaj   +1 more source

A redox sensor in protein kinase A regulatory subunit Iα regulates vasodilation and protects against hypertension. [PDF]

open access: yesRedox Biol
Rudyk O   +10 more
europepmc   +1 more source

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