Results 231 to 240 of about 115,625 (290)

Increases in skin perfusion and blood oxygen in the non‐exercising human limbs during exercise in the heat: Implications for control of circulation

open access: yesExperimental Physiology, EarlyView.
Abstract Blood flow in the inactive limb tissues and skin is widely thought to decline during incremental exercise to exhaustion due to augmented sympathoadrenal vasoconstrictor activity, but direct evidence to support this view is lacking. Here, we investigated the inactive‐forearm haemodynamic (Q̇forearm${\dot{Q}}_{\mathrm{forearm}}$) and oxygenation
Steven J. Trangmar   +1 more
wiley   +1 more source

Human adaptation to high‐altitude: A contemporary comparison of the oxygen cascade in Andean, Tibetan and Ethiopian highlanders

open access: yesExperimental Physiology, EarlyView.
Abstract Human populations native to high altitude have evolved distinct physiological adaptations to chronic hypoxia. This adaptation is evident in the O2 transport cascade. In this review, with brief inclusion of the related genetic adaptations, we compare the O2 cascade across three well‐characterized high‐altitude populations: Andeans (Aymara and ...
Ayechew A. Getu   +5 more
wiley   +1 more source

Sodium–glucose cotransporter 2 inhibitors for hypertension in cardiovascular–kidney–metabolic syndrome

open access: yesExperimental Physiology, EarlyView.
Abstract The antihypertensive mechanism of sodium–glucose cotransporter 2 (SGLT2) inhibitors has been traditionally attributed to osmotic diuresis. However, emerging evidence reveals multifaceted mechanisms beyond diuresis, including regulation of the renin–angiotensin–aldosterone system, sympathetic nervous system suppression, ion homeostasis ...
Chunxiang Xu   +5 more
wiley   +1 more source

Hypoxic microenvironment and pulmonary hypertension. [PDF]

open access: yesRespir Res
Mu T   +6 more
europepmc   +1 more source

Imposed expiratory resistance, dynamic hyperinflation and locomotor power and fatigue

open access: yesExperimental Physiology, EarlyView.
Abstract Expiratory flow limitation results in dynamic hyperinflation, dyspnoea and premature exercise intolerance. We aimed to measure whether expiratory resistance reduces locomotor power via limiting maximal voluntary motor activity, exacerbating muscle fatigue, or both.
Jonathan Cunha   +4 more
wiley   +1 more source

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