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Hypoxic Pulmonary Vasoconstriction
Physiological Reviews, 2012It has been known for more than 60 years, and suspected for over 100, that alveolar hypoxia causes pulmonary vasoconstriction by means of mechanisms local to the lung. For the last 20 years, it has been clear that the essential sensor, transduction, and effector mechanisms responsible for hypoxic pulmonary vasoconstriction (HPV) reside in the pulmonary
Sylvester, J. T. +3 more
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Hypoxic pulmonary vasoconstriction
Journal of Applied Physiology, 2005Humans encounter hypoxia throughout their lives. This occurs by destiny in utero, through disease, and by desire, in our quest for altitude. Hypoxic pulmonary vasoconstriction (HPV) is a widely conserved, homeostatic, vasomotor response of resistance pulmonary arteries to alveolar hypoxia.
Rohit Moudgil +2 more
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Vasoconstriction and long-term headache in reversible cerebral vasoconstriction syndrome
Journal of Neurology, 2022Angiographic vasoconstriction in reversible cerebral vasoconstriction syndrome (RCVS) is often undetectable at symptom onset and the diagnosis relies on clinical presentation. Although thunderclap headache is a hallmark feature of RCVS, the incidence and predictors of long-term headaches (LTH) are incompletely understood.
Neha Kumar +3 more
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Mechanisms of vasoconstriction
American Heart Journal, 1991The contractility of vascular smooth muscle cells is controlled in a complex manner by both extracellular and intracellular messages. The vascular endothelium does not simply act as a physical barrier between the blood and smooth muscle cells, it integrates intravascular signals and controls the contractility of underlying smooth muscle cells by way of
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Hypoxic pulmonary vasoconstriction
General Pharmacology: The Vascular System, 1999Hypoxic vasoconstriction is unique to pulmonary circulation. The pulmonary response is part of a self-regulatory mechanism by which pulmonary capillary blood flow is automatically adjusted to alveolar ventilation for maintaining the optimal balance of ventilation and perfusion. In pathological conditions, hypoxic pulmonary vasoconstriction may occur as
Marc Bardou +3 more
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Postgraduate Medicine, 1960
Vasoconstriction of some degree is almost always present in the skin of the extremities; it is more active in peripheral sites. Vasoconstriction may be caused by stimuli of central origin or by reflexive responses to peripheral stimuli. Cold and posture are the most significant causes of reflexive stimuli. Abnormal vasoconstriction is seen in Raynaud's
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Vasoconstriction of some degree is almost always present in the skin of the extremities; it is more active in peripheral sites. Vasoconstriction may be caused by stimuli of central origin or by reflexive responses to peripheral stimuli. Cold and posture are the most significant causes of reflexive stimuli. Abnormal vasoconstriction is seen in Raynaud's
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Cold vasoconstriction and vasodilatation
The Irish Journal of Medical Science, 19511. When the finger is immersed in water between 0° and 6°C. the initial vasoconstriction is usually, and the subsequent vasoconstrictions are occasionally, sudden in onset and complete in degree. 2. The initial vasodilatation is usually rapid in onset. 3.
A. D. M. Greenfield +2 more
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Cholinergic Vasoconstriction in the Eye
Journal of Ocular Pharmacology and Therapeutics, 1990Data is presented to support a physiologic vasoconstrictor function of the parasympathetic nervous system in the anterior uvea of the eye. Studies in rabbits, cats and monkeys demonstrate that stimulation of the parasympathetic nerve fibers running with the oculomotor nerve to the eye induces a reduction in blood flow of the iris and in rabbits in the ...
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Endothelin and Vasoconstriction
1991We investigated the effect of endothelin-1 (ET) on cytosolic free Ca2+ concentration ( [Ca2+]i) and intracellular Ca2+ store in vascular smooth muscle cells (VSMCs). Using quin2 microfluorometry, effects of ET on [Ca2+]i were investigated in rat aortic VSMCs in primary culture.
Hisashi Kai +3 more
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Cerebral vasoconstriction in toxemia
Neurology, 1987Three patients with toxemia developed acute neurologic deterioration postpartum. In all, cerebral angiography revealed widespread arterial vasoconstriction. Cerebral vasoconstriction may be an important cause of neurologic complications in toxemia.
K. L. Lewis +6 more
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