Results 31 to 40 of about 112,252 (265)

Hepatic and Pulmonary Vasoactive Response Triggered by Potentially Hazardous Chemicals After Passing Through the Gut Mucosa

Diagnostics
Background/Objectives: In a previous study, we observed significantly prolonged hepatic and pulmonary first-pass transit times (TTs) for 99mTc-pertechnetate absorbed through the colorectal mucosa during per-rectal portal scintigraphy (PRPS).
Mircea Dragoteanu, Ștefan Tolea, Ioana Duca, Raluca Mititelu, Kalevi Kairemo   +4 more
doaj   +1 more source

Vasoconstriction by Noradrenaline in the Brain [PDF]

Nature New Biology, 1973
IN view of the present controversy, recently voiced in your journal1–3 and elsewhere4,5, concerning a significant vasoconstrictor action of noradrenaline (NA) applied microiontophoretically in the brain, it seems worth pointing out that the required experiments, that is direct applications of NA to cerebral vessels in cats, have been performed by ...
openaire   +2 more sources

Vascular Contributions to Migraine: Time to Revisit?

Frontiers in Cellular Neuroscience, 2018
Migraine is one of the most prevalent and disabling neurovascular disorders worldwide. However, despite the increase in awareness and research, the understanding of migraine pathophysiology and treatment options remain limited.
Bianca N. Mason, Andrew F. Russo, Andrew F. Russo, Andrew F. Russo   +3 more
doaj   +1 more source

Limited AT1 Receptor Internalization Is a Novel Mechanism Underlying Sustained Vasoconstriction Induced by AT1 Receptor Autoantibody From Preeclampsia

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Angiotensin II type 1 receptor (AT1R) autoantibody (AT1‐AA) was first identified as a causative factor in preeclampsia. Unlike physiological ligand angiotensin II (Ang II), AT1‐AA can induce vasoconstriction in a sustained manner, causing a ...
Jingwei Bian, Jinghui Lei, Xiaochen Yin, Pengli Wang, Ye Wu, Xiaoli Yang, Li Wang, Suli Zhang, Huirong Liu, Michael L. X. Fu   +9 more
doaj   +1 more source

Constrictor responses of cerebral resistance arterioles in male and female rats exposed to prenatal alcohol

Physiological Reports, 2021
While it is known that dilation of cerebral arterioles to NOS‐dependent agonists is impaired in rats exposed to prenatal alcohol, no studies have examined the influence of prenatal alcohol on constrictor response of cerebral arterioles.
Partha S. Saha, Tiffany M. Knecht, Denise M. Arrick, Michael J. Watt, Jamie L. Scholl, William G. Mayhan   +5 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Vasoconstriction Response to Mental Stress in Sickle Cell Disease: The Role of the Cardiac and Vascular Baroreflexes

Frontiers in Physiology, 2021
Recent studies have shown that individuals with sickle cell disease (SCD) exhibit greater vasoconstriction responses to physical autonomic stressors, such as heat pain and cold pain than normal individuals, but this is not the case for mental stress (MTS)
Wanwara Thuptimdang, Payal Shah, Maha Khaleel, John Sunwoo, Saranya Veluswamy, Roberta M. Kato, Thomas D. Coates, Michael C. K. Khoo   +7 more
doaj   +1 more source

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source

Reversible Cerebral Vasoconstriction Syndrome Presenting as Transient Vessel Wall Enhancement on Contrast-Enhanced Fluid-Attenuated Inversion Recovery Images: A Case Report and Literature Review

대한영상의학회지, 2020
Reversible cerebral vasoconstriction syndrome (RCVS) is a clinical and radiological syndrome with primary features that include hyperacute onset of severe headache and segmental vasoconstriction of the cerebral arteries, which resolve within 3 months ...
Sun Ah Heo, Eun Soo Kim, Yul Lee
doaj   +1 more source

CFTR deficiency aggravates Ang II induced vasoconstriction and hypertension by regulating Ca𝟐+ influx and RhoA/Rock pathway in VSMCs

Frontiers in Bioscience-Landmark, 2021
Background: Cystic fibrosis transmembrane conductance regulator (CFTR) has been associated with vascular tone and blood pressure (BP), however, its role in the genesis of hypertension remains elusive.
Liyan Zhao, Feng Yuan, Ni Pan, Yun Yu, Hanyan Yang, Yaosheng Liu, Ruomei Wang, Bin Zhang, Guanlei Wang   +8 more
doaj   +1 more source