Results 81 to 90 of about 184,374 (299)

Contraindicated drug–drug interactions and associated adverse drug reactions in an observational cohort study of 4543 paediatric hospitalized patients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Background and Purpose Drug–drug interactions (DDIs) are associated with an increased risk of adverse drug reactions (ADRs). Hospitalized children are particularly vulnerable to DDIs and ADRs due to polypharmacy, frequent use of unlicensed or off‐label medications, and dosing regimens often extrapolated from adult data.
Emilie Laval   +6 more
wiley   +1 more source

Cutaneous Ischaemia Following Terlipressin Therapy for Hepatorenal Syndrome [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2018
Hepatorenal Syndrome (HRS) is a potentially fatal complication of hepatic failure and portal hypertension. Among the various treatments available including octreotide, midodrine and albumin, the current standard of care for stable patients is ...
Aneesh Basheer   +3 more
doaj   +1 more source

Alpha1 -adrenergic stimulation selectively enhances endothelium-mediated vasodilation in rat cremaster arteries. [PDF]

open access: yes, 2018
We have systematically investigated how vascular smooth muscle α1 -adrenoceptor activation impacts endothelium-mediated vasodilation in isolated, myogenically active, rat cremaster muscle 1A arteries.
Braun, Andrew P   +5 more
core   +1 more source

Macrophages come to mind as keys to cognitive decline [PDF]

open access: yes, 2016
Cognitive impairment, an underappreciated consequence of hypertension, is linked to cerebral arteriolar disease through poorly defined mechanisms. A study by Faraco et al.
D.G. Harrison   +5 more
core   +1 more source

Scalable desolvation synthesis, storage stability, and comprehensive biophysical characterization of human hemoglobin nanoparticles as a potential hemoglobin‐based oxygen carrier

open access: yesBiotechnology Progress, EarlyView.
This work describes the development of human hemoglobin nanoparticles using an anti‐solvent precipitation synthesis method as a potential next generation hemoglobin‐based oxygen carrier. The hemoglobin nanoparticles are uniform in size and shape, hemocompatible, stable at various storage conditions, and demonstrate a scalable synthesis technique ...
Alisyn Greenfield, Andre F. Palmer
wiley   +1 more source

Flap perfusion of superficial split flap design for guided bone regeneration: A case report with ultrasonography

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background Effective flap management is crucial for successful bone regeneration procedures. Traditional flap release has been performed by the deep split design; recently, the superficial split design revives for its proposed anatomical and biomechanical advantages.
Oscar Durán‐Garnica   +4 more
wiley   +1 more source

Potentiating TMEM16A does not stimulate airway mucus secretion or bronchial and pulmonary arterial smooth muscle contraction

open access: yesFASEB BioAdvances, 2020
The calcium‐activated chloride channel (CaCC) TMEM16A enables chloride secretion across several transporting epithelia, including in the airways. Additional roles for TMEM16A have been proposed, which include regulating mucus production and secretion and
Henry Danahay   +14 more
doaj   +1 more source

Studying the cutaneous microcirculatory response during upper-limb exercise in healthy, older, sedentary people [PDF]

open access: yes, 2012
This study investigated changes incurred in cutaneous skin blood flux (SKBF) in the superficial veins of the lower limb by upper limb exercise training in the form of arm-cranking in 14 healthy participants over the age of 50 years. Changes in cutaneous
Klonizakis, Markos
core   +1 more source

Feasibility and Safety of Distal Transradial Access in Patients With Out‐of‐Hospital Cardiac Arrest Undergoing Emergency PCI: A Single‐Center Retrospective Study

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Distal transradial access (dTRA) has gained attention for its lower risk of vascular complications compared to conventional transradial access (TRA). However, its feasibility and safety in patients with out‐of‐hospital cardiac arrest (OHCA) undergoing emergency percutaneous coronary intervention (PCI) remain uncertain.
Shiori Kawakami   +9 more
wiley   +1 more source

Cardiovascular and hepatic toxicity of cocaine: potential beneficial effects of modulators of oxidative stress [PDF]

open access: yes, 2015
Oxidative stress (OS) is thought to play an important role in the pharmacological and toxic effects of various drugs of abuse. Herein we review the literature on the mechanisms responsible for the cardiovascular and hepatic toxicity of cocaine with ...
Antonilli, Letizia   +5 more
core   +4 more sources

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