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Chapter 8. Vasodilator and Vasoconstrictor Agents

Annual Reports in Medicinal Chemistry, 1969
Publisher Summary This chapter presents an overview of vasodilator and vasoconstrictor agents. Many drugs with diverse pharmacological actions ultimately alter vascular tone. Antihypertensive agents as well as drugs used to treat peripheral vascular diseases are among those that reduce vascular tone.
F.P. Hauck, C.N. Gillis
exaly   +2 more sources

VASOCONSTRICTOR AGENTS IN LOCAL-ANÆSTHETIC PREPARATIONS

Lancet, The, 1972
F Reynolds
exaly   +6 more sources

AMPLIFICATION BY SEROTONIN OF RESPONSES TO OTHER VASOCONSTRICTOR AGENTS IN THE RAT TAIL ARTERY

Clinical and Experimental Pharmacology and Physiology, 1989
SUMMARY1. A low concentration of serotonin (3 nmol/L), which did not exert a direct vasoconstrictor action, amplified the responses to certain other vasoconstrictor agents (α1‐adrenoceptor agonists, KCl, ATP and vasopressin) in isolated perfused segments of the rat tail artery.2.
X-H Xiao, M J Rand
exaly   +3 more sources

Vasoconstrictor Responses to Vasopressor Agents in Human Pulmonary and Radial Arteries

Anesthesiology, 2014
Abstract Background: Vasopressor drugs, commonly used to treat systemic hypotension and maintain organ perfusion, may also induce regional vasoconstriction in specialized vascular beds such as the lung. An increase in pulmonary vascular tone may adversely affect patients with pulmonary hypertension or right heart ...
Christine E Wright, James A Angus, Paul Soeding   +2 more
exaly   +3 more sources

VASOCONSTRICTOR AGENTS IN LOCAL-ANAESTHETIC PREPARATIONS

Lancet, The, 1972
exaly   +4 more sources

Beta-adrenergic Blocking Agents and Dental Vasoconstrictors

Dental Clinics of North America, 2010
A clinically significant interaction between epinephrine or levonordefrin with nonselective beta-adrenergic blocking agents, although apparently rare in the dental setting, is potentially serious and can lead to significant hypertension with a concomitant reflex bradycardia.
Elliot V, Hersh, Helen, Giannakopoulos
openaire   +2 more sources

Circulatory responses to vasoconstrictor agents during passive heating in the rat

Journal of Applied Physiology, 1990
The purpose of this study was to determine the actions of several pharmacological agents on the circulatory system, and more specifically on the superior mesenteric vascular bed, in response to environmental heat stress in chloralose-anesthetized rats.
K C, Kregel, C V, Gisolfi
openaire   +2 more sources

Termination of migraine headache by a new anti‐inflammatory vasoconstrictor agent

Clinical Pharmacology & Therapeutics, 1965
Indomethacin, a new nonsteroid anti‐inflammatory agent causes headache, a marked decrease in cerebrospinal fluid pressure, and an increase in retinal arterial pressure, while it produces little and inconstant change in the pressure of the carotid and brachial arteries.
F, SICUTERI, S, MICHELACCI, B, ANSELMI
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Effect of severe hypoxia on the pulmonary vascular response to vasoconstrictor agents

Journal of Applied Physiology, 1981
When isolated blood-perfused pig lungs are exposed to inspired O2 tensions (PIO2) below 30 Torr, hypoxic pulmonary vasoconstriction is transient. To determine whether this transience is caused by a decrease in the amount of ATP available for maintenance of smooth muscle contraction, we compared normoxic (PIO2 = 100 Torr) and hypoxic (PIO2 = 10 Torr ...
A L, Harabin, M D, Peake, J T, Sylvester
openaire   +2 more sources